CD170 (Siglec F) Monoclonal Antibody (1RNM44N), Brilliant Violet™ 605, eBioscience™, Invitrogen™
Rat Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
CD170 (Siglec F)
Concentration
0.2 mg/mL
Classification
Monoclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with BSA and 0.09% sodium azide; pH 7.2
Gene Alias
CD170; CD33 antigen-like 2; CD33L2; mSiglec-F; OB-binding protein 2; OBBP2; OB-BP2; Obesity-binding protein 2; sialic acid binding Ig like lectin 5; sialic acid binding Ig-like lectin 5; sialic acid binding Ig-like lectin F; sialic acid-binding Ig-like lectin 5; Sialic acid-binding Ig-like lectin F; sialic acid-binding immunoglobulin-like lectin 5; sialic acid-binding lectin Siglec-F; Siglec; SIGLEC5; siglec-5; Siglecf; Siglec-F
Gene Symbols
Siglecf
Primary or Secondary
Primary
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Clone
1RNM44N
Applications
Flow Cytometry
Conjugate
Brilliant Violet 605
Host Species
Rat
Target Species
Mouse
Gene Accession No.
Q920G3
Gene ID (Entrez)
233186
Isotype
IgG2a κ
Purification Method
Affinity chromatography
Gene
Siglecf
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Description
- SIGLEC5 is a putative adhesion molecule that mediates sialic-acid dependent binding to cells
- This protein binds equally to alpha2,3-linked and alpha2,6-linked sialic acid
- The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface
- This molecule is expressed by monocytic/myeloid lineage cells
- SIGLEC5 is found at high levels in peripheral blood leukocytes, spleen, bone marrow and at lower levels in lymph node, lung, appendix, placenta, pancreas and thymus
- It is expressed by monocytes and neutrophils but absent from leukemic cell lines representing early stages of myelomonocytic differentiation.