200020265

HPa1 Monoclonal Antibody (C3), Invitrogen™

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

HPa1

Concentration

1 mg/mL

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Alias

Endo-glucoronidase, endoglycosidase heparanase, HEP, Heparanase, Heparanase 50 kDa subunit, Heparanase 8 kDa subunit, Heparanase-1, heparanase-like, Hpa, HPA1, HPR1, HPSE, HPSE1, HSE1

Gene Symbols

HPSE

Isotype

IgG2b κ

Purification Method

Protein A/G

Gene

HPSE

Clone

C3

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate

Unconjugated

Host Species

Mouse

Target Species

Human, Rat

Gene Accession No.

Q71RP1, Q9Y251

Gene ID (Entrez)

10855, 64537

Immunogen

Recombinant Rat HPSE protein, Arg40-Pro188 (Accession #Q71RP1)

Primary or Secondary

Primary

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

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Description

  • Stem cells offer a therapeutic promise for many diseases
  • In the case of diabetes, stem cells offer the promise that beta cells may be generated ex vivo for the possible transplantation and cure of Type I diabetes (Couri CE, et al
  • )
  • For this to happen, stem cells will need to be isolated and expanded, they will need to be differentiated toward the beta cell lineage, and the differentiated cell progeny used for transplantation may need to be isolated from complex cell mixtures following differentiation
  • Appropriate markers targeting cell surface molecules on developing and mature pancreatic cells will be required for such research.