EB1 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
EB1
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Conjugate
Unconjugated
Host Species
Rabbit
Target Species
Human, Porcine
Gene Accession No.
Q15691
Gene ID (Entrez)
22919, 733687
Immunogen
Recombinant Human MAPRE1 protein, Ala2-Tyr268 (Accession #Q15691)
Primary or Secondary
Primary
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Concentration
0.5 mg/mL
Classification
Polyclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4
Gene Alias
5530600P05Rik, adenomatosis polyposis coli binding protein Eb1, adenomatous polyposis coli-binding protein EB1, AI462499, AI504412, APC-binding protein EB1, AW260097, BIM1p, D2Ertd459e, Eb1, end-binding protein 1, Mapre1, MGC117374, MGC129946, microtubule associated protein RP/EB family member 1, Microtubule-associated protein RP/EB family member 1, microtubule-associated protein RP/EB family member 1-like protein, microtubule-associated protein, RP/EB family, member 1
Gene Symbols
Mapre1
Isotype
IgG
Purification Method
Protein A
Gene
Mapre1
Related Products
Description
- EB1 family proteins are evolutionarily conserved proteins that bind microtubule plus-ends and centrosomes and regulate the dynamics and organization of microtubules
- The MAPRE genes encode the EB1 family proteins
- The human MAPRE genes MAPRE1, MAPRE2, and MAPRE3 code for EB1, RP1, and EBF3 proteins, respectively
- EB1 family members appear to be expressed ubiquitously
- The EB1 (MAPRE1) gene, at 20q11
- 2, is fused to MLL in an adult patient with pro-B acute lymphoblastic leukemia
- EB1 is a microtubule-associated protein that interacts with the colorectal adenomatous polyposis coli tumor-suppressor protein and plays important roles in regulating microtubule dynamics, cell polarity, and chromosome stability.