23-600-250UG
MilliporeSigma™ anti-COX2, C-Terminal, Polyclonal
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 23-600-250UG-Each-of-1 | In Stock | ₹ 45,464.76 |
23-600-250UG - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,464.76
GST (18%): ₹ 8,183.657
Total Price: ₹ 53,648.417
Antigen
COX2, C-Terminal
Classification
Polyclonal
Formulation
In PBS, 0.1% BSA, pH 7.4.
Immunogen
a synthetic peptide corresponding to a 17-amino acid sequence near the C-terminus of human COX2
Regulatory Status
RUO
Test Specificity
Recognizes COX2. Does not cross-react with COX1.
Content And Storage
−20°C
Isotype
IgG
Applications
ELISA, Immunoblot, Immunoblot
Conjugate
Unconjugated
Host Species
Rabbit
Quantity
50 μg
Primary or Secondary
Primary
Target Species
Bovine, Human, Mouse, Rat, Sheep
Form
Purified
Related Products
Description
- Specifically detects COX2, C-Terminal Clone: in Bovine, Human, Mouse, Rat, Sheep samples, and it is validated for ELISA, Immuno Blotting COX proteins are membrane-associated heme proteins that have cyclooxygenase and peroxidase activities
- These enzymes are targets of NSAID (Nonsteroidal anti-inflammatory drugs) such as aspirin
- Prostaglandins (PGs) formed by the enzymatic activity of COX1 are primarily involved in the regulation of homeostatic functions throughout the body, whereas PGs formed by COX2 primarily mediate pain, fever, and inflammation
- COX2 is induced by a wide variety of stimuli and was initially identified as an immediate-early growth response gene
- In addition, COX2 expression is markedly increased in 85-90% of human colorectal adenocarcinomas, whereas COX1 levels remain unchanged
- COX2 may be involved in angiogenesis, as new angiogenic endothelial cells express the inducible COX2 while normal blood vessels express COX1.