36-260-0

GRP94 Polyclonal Antibody, Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each of 1 36-260-0-Each-of-1 In Stock ₹ 44,500.00

36-260-0 - Each of 1

₹ 44,500.00

In Stock

Quantity

1

Base Price: ₹ 44,500.00

GST (18%): ₹ 8,010.00

Total Price: ₹ 52,510.00

Antigen

GRP94

Classification

Polyclonal

Conjugate

Unconjugated

Gene

HSP90B1

Gene Alias

108K heat shock protein; 108K HSP; 94 kDa glucose-regulated protein; 94 kDa glucose-regulated protein {ECO:0000250; 98 kDa protein kinase; ecgp; endoplasmic reticulum resident protein 99; Endoplasmin; endoplasmin {ECO:0000250; endoplasmin-like protein; endothelial cell (HBMEC) glycoprotein; epididymis luminal protein 35; epididymis secretory sperm binding protein Li 125m; ERp99; glucose-regulated protein; glucose-regulated protein GRP94; glucose-regulated protein GRP94 precursor; GP96; gp96 homolog; gp96/GRP94; GRP94; GRP-94; heat shock 108 kDa protein; heat shock protein 108; heat shock protein 108.; heat shock protein 90 beta family member 1; heat shock protein 90 kDa beta member 1; heat shock protein 90 kDa beta member 1 {ECO:0000250; heat shock protein 90, beta (Grp94), member 1; heat shock protein 90, beta, member 1; heat shock protein 90kDa beta (Grp94), member 1; heat shock protein 90kDa beta family member 1; heat shock protein 90kDa beta family member 1 L homeolog; heat shock protein 90kDa beta, member 1; heat shock protein gp96; HEL35; HEL-S-125m; HSP 108; hsp108; HSP90 beta; hsp90b1; hsp90b1 {ECO:0000250; hsp90b1.L; Polymorphic tumor rejection antigen 1; PPK 98; Ppk 98; a protein kinase; ppk98; stress-inducible tumor rejection antigen gp96; TA-3; Targ2; tra1; Tra-1; transferrin-binding protein; transforming growth factor alpha regulated gene 2; tumor rejection antigen; tumor rejection antigen (gp96) 1; tumor rejection antigen 1; Tumor rejection antigen gp96; UniProtKB:P08113}; XELAEV_18017384mg

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

22027, 362862, 7184

Content And Storage

-20°C

Form

Liquid

Applications

ELISA, Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot

Concentration

0.25 mg/mL

Formulation

PBS with 0.1% sodium azide; pH 7.4

Gene Accession No.

P08113, P14625, Q66HD0

Gene Symbols

HSP90B1

Immunogen

Synthetic peptide derived from the N-terminal region of the mouse and human gp96 protein

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Description GRP94 is a 803 amino acid protein belonging to the heat shock protein 90 family
  • It acts as a molecular chaperone that functions in the processing and transport of secreted proteins
  • GRP94 and its N-terminal fragment stimulates CTL expansion and maturation of human monocyte-derived dendritic cells (MDDC)
  • It plays a central role in innate as well as acquired immunity, maturation and chemotaxis of dendritic cells, Ab production, cross-priming, as a potential marker in breast cancer and is a peptide acceptor in endoplasmic reticulum and an accessory to peptide loading of MHC class I molecules
  • Expression of GRP94 suppressed A23187-induced apoptosis and stabilized calcium homeostasis
  • GRP94 is expressed in melanoma or liver metastases of colon carcinoma cells, human gastric carcinoma BGC-823 cells.