Connexin 31 Polyclonal Antibody, Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 36-510-0-Each-of-1 | In Stock | ₹ 38,270.00 |
36-510-0 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 38,270.00
GST (18%): ₹ 6,888.60
Total Price: ₹ 45,158.60
Antigen
Connexin 31
Classification
Polyclonal
Conjugate
Unconjugated
Gene
GJB3
Gene Alias
Cnx31; connexin 31; connexin-31; Cx31; Cxn-31; D4Wsu144e; DFNA2; DFNA2B; EKV; Gap junction beta-3 protein; gap junction membrane channel protein beta 3; gap junction protein beta 3; gap junction protein, beta 3; gap junction protein, beta 3, 31kDa; Gjb3; Gjb-3
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
14620, 2707
Content And Storage
Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (PFA fixed), Immunoprecipitation, Western Blot
Concentration
0.25 mg/mL
Formulation
PBS with 0.1% sodium azide; pH 7.4
Gene Accession No.
O75712, P28231
Gene Symbols
GJB3
Immunogen
Synthetic peptide derived from the C-terminal region of mouse connexin 31 protein
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- This antibody reacts with the ∽32 kDa mouse Connexin 31 on Western blots; the band observed at ∽62 kDa is probably due to dimerization of Connexin 31
- Several higher bands of unknown origin are observed in western blots of mouse skin homogenates
- Gap junctions are conduits that allow the direct cell-to-cell passage of small cytoplasmic molecules, including ions, metabolic intermediates, and second messengers, and thereby mediate intercellular metabolic and electrical communication
- Gap junction channels consist of connexin protein subunits, which are encoded by a multigene family
- GJBs (gap-junction proteins or connexins) play crucial functional roles associated with these channels
- Defects in GJB3 have been linked to erythrokeratodermia variabilis (EKV) is an autosomal dominant genodermatosis characterized by transient figurate red patches or hyperkeratosis
- Mutations in GJB2 have also been associated with genetically derived hearing impairments, including autosomal recessive nonsyndromic deafness.