36-550-0

IRAK4 Polyclonal Antibody, Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each of 1 36-550-0-Each-of-1 In Stock ₹ 38,270.00

36-550-0 - Each of 1

₹ 38,270.00

In Stock

Quantity

1

Base Price: ₹ 38,270.00

GST (18%): ₹ 6,888.60

Total Price: ₹ 45,158.60

Antigen

IRAK4

Classification

Polyclonal

Conjugate

Unconjugated

Gene

IRAK4

Gene Alias

8430405M07Rik; 9330209D03Rik; interleukin 1 receptor associated kinase 4; interleukin-1; interleukin-1 receptor-associated kinase 4; IPD1; Irak4; IRAK-4; NY-REN-64; REN64; renal carcinoma antigen NY-REN-64

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

266632, 51135

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

0.25 mg/mL

Formulation

PBS with 0.1% sodium azide; pH 7.4

Gene Accession No.

Q8R4K2, Q9NWZ3

Gene Symbols

IRAK4

Immunogen

Synthetic peptide derived from the N-terminal region of the human IRAK4 (IL-1 receptor associated kinase 4) protein.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • IL-1 receptor associated kinases (IRAKs) are serine/threonine kinases involved in signaling via Toll/IL-1 pathways
  • Overexpression of IRAK-4 activates NF-kappa-B and MAPK pathways
  • IRAK-4 interacts with and phosphorylates IRAK-1
  • IRAK-4-deficient animals are completely resistant to the challenge with LPS
  • Animals and humans lacking IRAK-4 are impaired in their responses to viral and bacterial challenges
  • Members in IRAK/Pelle family play a central role in IL-1R/TLR mediated inflammatory responses and in innate immunity.