CD103 (Integrin alpha E) Monoclonal Antibody (2E7), Brilliant Ultra Violet™ 615, eBioscience™, Invitrogen™
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 36-610-3180-Each-of-1 | In Stock | ₹ 17,355.00 |
36-610-3180 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 17,355.00
GST (18%): ₹ 3,123.90
Total Price: ₹ 20,478.90
Antigen
CD103 (Integrin alpha E)
Classification
Monoclonal
Concentration
0.2 mg/mL
Formulation
PBS with BSA and 0.09% sodium azide, pH 7.2
Gene Accession No.
Q60677
Gene Symbols
Itgae
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
16407
Content And Storage
4°, C, store in dark, DO NOT FREEZE!
Isotype
IgG
Applications
Flow Cytometry
Clone
2E7
Conjugate
Brilliant Ultraviolet 615
Gene
Itgae
Gene Alias
A530055J10, alpha-E1, alpha-M290, aM290, antigen CD103, antigen CD103, human mucosal lymphocyte antigen 1, alpha polypeptide, CD103, DC, DCs, HML-1 antigen, human mucosal lymphocyte antigen 1, alpha polypeptide, HUMINAE, integrin alpha E, integrin alpha E, epithelial-associated, integrin alpha E1, epithelial-associated, integrin alpha M290, Integrin alpha-E, Integrin alpha-E heavy chain, Integrin alpha-E light chain, Integrin alpha-IEL, integrin subunit alpha E, integrin, alpha E, integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1, alpha polypeptide), integrin, alpha E, epithelial-associated, Intregrin alpha E2, Itgae, MGC141996, Mucosal lymphocyte 1 antigen
Host Species
Armenian Hamster
Quantity
25 μg
Primary or Secondary
Primary
Target Species
Mouse
Form
Liquid
Related Products
Description
- CD103 (ITGAE, Integrin alpha E) is molecule that is expressed on mucosa-associated T lymphocytes and activated cells and on subet of TGF beta -1 cells
- In particular, CD103 includes a 150kDa alpha chain and a 120kDa beta chain
- CD103 is expressed by 0.5 to 2% of resting lymphocytes in peripheral blood and lymphoid organs
- CD103 antibody stains a few bone marrow cells and, rarely, peripheral blood lymphocytes
- CD103 is part of the integrin family which are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain
- ITGAE encodes an I-domain-containing alpha integrin that undergoes post-translational cleavage in the extracellular domain, yielding disulfide-linked heavy and light chains
- In combination with the beta 7 integrin, CD103 protein forms the E-cadherin binding integrin known as the human mucosal lymphocyte-1 antigen
- CD103 is preferentially expressed in human intestinal intraepithelial lymphocytes (IEL), and in addition to a role in adhesion, it may serve as an accessory molecule for IEL activation
- Diseases associated with CD103 dysfunction include hairy cell leukemia and splenic marginal zone lymphoma.