37-604-5482
CD45.2 Monoclonal Antibody (104), Brilliant Ultra Violet™ 661, eBioscience™, Invitrogen™
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 37-604-5482-Each-of-1 | In Stock | ₹ 35,867.00 |
37-604-5482 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 35,867.00
GST (18%): ₹ 6,456.06
Total Price: ₹ 42,323.06
Antigen
CD45.2
Classification
Monoclonal
Concentration
0.2 mg/mL
Formulation
PBS with BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.
P06800
Gene Symbols
Ptprc
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
19264
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Isotype
IgG2a κ
Applications
Flow Cytometry
Clone
104
Conjugate
Brilliant Ultraviolet 661
Gene
Ptprc
Gene Alias
B220; Cd45; CD45 antigen; CD45R; GP180; LCA; L-CA; leukocyte common antigen; loc; LY5; Ly-5; lymphocyte antigen 5; lymphocyte common antigen; Lyt-4; protein tyrosine phosphatase, receptor type, C; Ptprc; Receptor-type tyrosine-protein phosphatase C; T200; T200 glycoprotein
Host Species
Mouse
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Mouse
Form
Liquid
Related Products
Description
- CD45.2 (LCA, leukocyte common antigen) is a receptor-type protein tyrosine phosphatase ubiquitously expressed in all nucleated hematopoietic cells, comprising approximately 10% of all surface proteins in lymphocytes
- CD45.2 glycoprotein is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases
- CD45.2 protein exists as multiple isoforms as a result of alternative splicing; these isoforms differ in their extracellular domains, whereas they share identical transmembrane and cytoplasmic domains
- These isoforms differ in their ability to translocate into the glycosphingolipid-enriched membrane domains and their expression depends on cell type and physiological state of the cell
- Besides the role in immunoreceptor signaling, CD45.2 is important in promoting cell survival by modulating integrin-mediated signal transduction pathway and is also involved in DNA fragmentation during apoptosis
- CD45RA is an isoform of the CD45 complex and has restricted expression between different subtypes of lymphoid cells.