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3854334

CD15 Mouse anti-Human, FITC, Clone: HI98 (also known as HIM1), BD

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

CD15

Applications

Flow Cytometry

Conjugate

FITC

Regulatory Status

RUO

Formulation

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Isotype

IgM κ

Purification Method

Affinity Purified

Clone

HI98 (also known as HIM1)

Classification

Monoclonal

Host Species

Mouse

Target Species

Human

Immunogen

Human Mononuclear Cells

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Description

  • Reacts with 3-fucosyl-N-acetyllactosamine (3-FAL), a 220kDa carbohydrate structure, also called X-hapten, SSEA-1, CD15 or Lewis X
  • 3-FAL is expressed on >95% of granulocytes, including neutrophils and eosinophils, and to a varying degree on monocytes, but not on lymphocytes or basophils
  • CD15 plays a role in mediating phagocytosis, bactericidal activity and chemotaxis
  • This antibody is also suitable for staining formalin-fixed, paraffin-embedded tissue sections without pretreatment
  • Since the Abs are recognizing a carbohydrate epitope (3-fucosyl-N-acetyllactosamine) they also should work across species and not only for human
  • Flow Cytometry