3968923
CD16 Mouse anti-Human, V450, Clone: 3G8, BD
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
CD16
Applications
Flow Cytometry
Conjugate
Violet Fluor 450 (V450)
Regulatory Status
RUO
Target Species
Baboon, Cynomolgus, Human, Rhesus Monkey
Immunogen
Human polymorphonuclear leukocytes
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Clone
3G8
Classification
Monoclonal
Host Species
Mouse
Research Discipline
Immunology
Formulation
Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Isotype
IgG1 κ
Purification Method
Affinity Purified
Description
FcRIII; Fc-gamma RIII; FCG3; FCGR3; FCGRIII; FcγRIII; IGFR3
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Description
- Reacts with the 50-65kDa transmembrane form of IgG Fc Receptor (FcγRIII), a human NK-cell-associated antigen
- CD16 is expressed on NK cells as well as macrophages and granulocytes
- Reports indicate that CD16 plays a role in signal transduction and NK cell activation
- 3G8 antibody blocks the binding of soluble immune complexes to granulocytes
- The antibody is conjugated to BD Horizon™ V450, which has been developed for use in multicolor flow cytometry experiments and is available exclusively from BD Biosciences
- It is excited by the Violet laser Ex max of 406nm and has an Em Max at 450nm
- Conjugates with BD Horizon™ V450 can be used in place of Pacific Blue™ conjugates
- Host Species: Mouse Clone: 3G8 Isotype: IgG1 κ Species Reactivity: Human Immunogen: Human polymorphonuclear leukocytes Flow Cytometry