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3969104

CD19 Mouse anti-Human, V450, Clone: HIB19, BD

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

CD19

Applications

Flow Cytometry

Conjugate

Violet Fluor 450 (V450)

Regulatory Status

RUO

Target Species

Human

Isotype

IgG1 κ

Purification Method

Affinity Purified

Clone

HIB19

Classification

Monoclonal

Host Species

Mouse

Research Discipline

Immunology

Formulation

Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Description

  • Reacts with the 95kDa type I transmembrane glycoprotein expressed during all stages of B-cell differentiation and maturation, except on plasma cells
  • CD19 is also present on follicular dendritic cells
  • It is not found on T cells or on normal granulocytes
  • CD19 plays a role in regulation of B-cell proliferation
  • It associates with the complement receptor 2 (CD21), TAPA-1 (CD81), Leu 13, and/or MHC class II to form a signal transduction complex on the surface of B cells
  • Anti-CD19 clone HIB19 partially blocks clone B43, another C19 mAb
  • The antibody is conjugated to BD Horizon™ V450, which has been developed for use in multicolor flow cytometry experiments and is available exclusively from BD Biosciences
  • It is excited by the Violet laser Ex max of 406nm and has an Em Max at 450nm
  • Conjugates with BD Horizon™ V450 can be used in place of Pacific Blue™ conjugates
  • Host Species: Mouse Clone: HIB19 Isotype: IgG1 κ Species Reactivity: Human Flow Cytometry