3972052
TCR β chain Hamster anti-Mouse, FITC, Clone: H57-597, BD
Hamster Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
TCR β chain
Concentration
0.5mg/mL
Classification
Monoclonal
Host Species
Hamster
Research Discipline
Immunology
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Isotype
IgG2
Purification Method
Affinity Purified
Clone
H57-597
Applications
Flow Cytometry
Conjugate
FITC
Regulatory Status
RUO
Target Species
Mouse
Immunogen
TCR affinity-purified from mouse T-cell hybridoma DO-11.10
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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Description
- Description The H57-597 antibody reacts with a common epitope of the β; chain of the T-cell Receptor (TCR) complex on α;β; TCR-expressing thymocytes and peripheral T lymphocytes and NK1.1+ thymocytes and NK-T cells of all mouse strains tested
- It does not react with γδ TCR-bearing T cells
- In the fetal and adult thymus, the TCR β; -chain may form homodimers or pair with the pre-TCR α; -chain on the surface of immature thymocytes before expression of the TCR α; -chain
- Plate-bound or soluble H57-597 antibody activates α;β; TCR-bearing T cells, and plate-bound mAb can induce apoptotic death.