40-240-0

Arfaptin 2 Polyclonal Antibody, Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each of 1 40-240-0-Each-of-1 In Stock ₹ 38,270.00

40-240-0 - Each of 1

₹ 38,270.00

In Stock

Quantity

1

Base Price: ₹ 38,270.00

GST (18%): ₹ 6,888.60

Total Price: ₹ 45,158.60

Antigen

Arfaptin 2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

ARFIP2

Gene Alias

2310002N04Rik; ADP ribosylation factor interacting protein 2; ADP-ribosylation factor interacting protein 2; ADP-ribosylation factor interacting protein 2 (arfaptin 2); ADP-ribosylation factor-interacting protein 2; Arfaptin 2; arfaptin-2; Arfip2; Partner of RAC1; partner of RAC1 (arfaptin 2); POR; POR1; Protein POR1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

23647, 293344, 76932

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

0.25 mg/mL

Formulation

PBS with 0.1% sodium azide; pH 7.4

Gene Accession No.

P53365, Q6AY65, Q8K221

Gene Symbols

ARFIP2

Immunogen

Synthetic peptide derived from the N-terminal region of the human Arfaptin 2 protein (ADP-ribosylation factor interacting protein 2, AFP2, Partner of Rac1, or POR1)

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Plays a role in constitutive metalloproteinase (MMP) secretion from the trans Golgi network
  • May have important functions during vesicle biogenesis at certain cargo subdomains, which could be predominantly utilized by secreted MMPs, such as MMP7 and MMP2 (PubMed:26507660)
  • Participates also in autophagy by regulating the starvation-depdendent trafficking of ATG9A vesicles which deliver the PI4-kinase to the autophagosome initiation site (PubMed:31204568)
  • In addition, plays a role in NF-kappa-B inhibition by interacting with IKBKB and IKBKG (PubMed:26296658)
  • [UniProt]