PCDGF Polyclonal Antibody, Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 40-340-0-Each-of-1 | In Stock | ₹ 40,050.00 |
40-340-0 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 40,050.00
GST (18%): ₹ 7,209.00
Total Price: ₹ 47,259.00
Antigen
PCDGF
Classification
Polyclonal
Conjugate
Unconjugated
Gene
GRN
Gene Alias
Acrogranin; CLN11; Epithelin precursor; Epithelin-1; Epithelin-2; GEP; Glycoprotein of 88 Kda; GP88; granulin; Granulin A; Granulin B; Granulin C; Granulin D; Granulin E; Granulin F; Granulin G; Granulin precursor; Granulin-1; Granulin-2; Granulin-3; Granulin-4; Granulin-5; Granulin-6; Granulin-7; granulin-epithelin; granulins; GRN; Paragranulin; PC cell-derived growth factor; PCDGF; PEPI; PGRN; proepithelin; Progranulin
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
2896
Content And Storage
-20°C
Form
Liquid
Applications
Immunoprecipitation, Western Blot
Concentration
0.25 mg/mL
Formulation
PBS with 0.1% sodium azide; pH 7.4
Gene Accession No.
P28799
Gene Symbols
GRN
Immunogen
Synthetic peptide derived from the C-terminal region of human PCDGF
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Granulins are a family of secreted, glycosylated peptides that are cleaved from a single precursor protein with 7.5 repeats of a highly conserved 12-cysteine granulin/epithelin motif
- The 88 kDa precursor protein, progranulin, is also called proepithelin and PC cell-derived growth factor
- Cleavage of the signal peptide produces mature granulin which can be further cleaved into a variety of active, 6 kDa peptides
- These smaller cleavage products are named granulin A, granulin B, granulin C, etc
- Epithelins 1 and 2 are synonymous with granulins A and B, respectively
- Both the peptides and intact granulin protein regulate cell growth
- However, different members of the granulin protein family may act as inhibitors, stimulators, or have dual actions on cell growth
- Granulin family members are important in normal development, wound healing, and tumorigenesis.