IFN gamma Monoclonal Antibody (XMG1.2), Brilliant Violet™ 605, eBioscience™, Invitrogen™
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 40-673-1180-Each-of-1 | In Stock | ₹ 15,575.00 |
40-673-1180 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 15,575.00
GST (18%): ₹ 2,803.50
Total Price: ₹ 18,378.50
Antigen
IFN gamma
Classification
Monoclonal
Concentration
0.2 mg/mL
Formulation
PBS with BSA and 0.09% sodium azide, pH 7.2
Gene Accession No.
P01580
Gene Symbols
IFNG
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
15978
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Isotype
IgG1 κ
Applications
Flow Cytometry
Clone
XMG1.2
Conjugate
Brilliant Violet 605
Gene
IFNG
Gene Alias
BoIFNG, cytokine, EGK_03901, gamma interferon, gamma interferon precursor, gamma-interferon, gamma-interferon precursor (AA -23 to 143), H-IFN-g, IFG, IFI, IFN gamma, IFN ?, Ifng, IFN-g, IFNG2, IFN-gamma, IFN-gamma precursor, IFN-y, IFN?, Immune interferon, interferon gamma, interferon gamma precursor, interferon gamma type 2, Interferon y, Interferon ?, interferon, gamma, interferon-gama, interferon-gamma, Interferon-gamma level, interferon-gamma precursor, Interferon?, M-IFN-g, R-IFN-g
Host Species
Rat
Quantity
25 μg
Primary or Secondary
Primary
Target Species
Mouse
Form
Liquid
Related Products
Description
- IFN gamma (Interferon gamma, Type II interferon) is a macrophage activation factor, and immune interferon that is produced primarily by T-lymphocytes and natural killer cells in response to antigens, mitogens, Staphylococcus enterotoxin B, phytohemaglutanin and other cytokines
- IFN gamma is a dimeric protein consisting of two 146 amino acid subunits
- IFN gamma is a glycoprotein that exists, functionally, as a homodimer of approximately 45 kDa
- On SDS-PAGE, IFN gamma appears as a combination of 25, 20 and minor 15.5 kDa bands as a result of differential glycosylation
- The biological activity of the IFN gamma homodimer is highly species specific
- Human IFN gamma does not show cross-reactivity with mouse
- IFN gamma function includes the following: antiviral activity, tumor antiproliferative activity, induction of class I and II MHC, macrophage activation, and enhanced immunoglobulin secretion by B lymphocytes
- IFN gamma is involved in cytokine regulation and also acts synergistically with other cytokines
- Activation of IFN gamma takes place through binding of IFN gamma receptor I and II, and activating the JAK-STAT pathway
- IFN gamma does not show any homology with IFN alpha or IFN beta but human IFN gamma shows about 40% sequence homology with mouse IFN gamma
- IFN gamma is upregulated by IL2, FGF basic, EGF and downregulated by vitamin D3 or DMN
- IFN gamma gene mutations are associated with aplastic anemia.