Connexin 45 Monoclonal Antibody (ZC014), Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 41-170-0-Each-of-1 | In Stock | ₹ 35,600.00 |
41-170-0 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 35,600.00
GST (18%): ₹ 6,408.00
Total Price: ₹ 42,008.00
Antigen
Connexin 45
Classification
Monoclonal
Concentration
0.5 mg/mL
Formulation
PBS with 0.1% sodium azide; pH 7.4
Gene Accession No.
P28229
Gene Symbols
GJC1
Immunogen
Synthetic peptide derived from the C-terminal region of the mouse connexin 45 protein
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Mouse
Product Type
Antibody
Isotype
IgG1 κ
Applications
ELISA, Immunohistochemistry (Frozen)
Clone
ZC014
Conjugate
Unconjugated
Gene
GJC1
Gene Alias
C130009G16Rik; Cnx45; connexin 45; connexin-45; CTC-296K1.4; CX45; Cxn-45; Gap junction alpha-7 protein; gap junction channel protein connexin 45; gap junction gamma-1 protein; gap junction membrane channel protein alpha 7; gap junction protein gamma 1; gap junction protein, gamma 1; gap junction protein, gamma 1, 45kDa; Gja7; Gja-7; GJC1
Host Species
Mouse
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
14615
Content And Storage
-20°C
Form
Liquid
Related Products
Description
- Gap junctions were first characterized by electron microscopy as regionally specialized structures on plasma membranes of contacting adherent cells
- These structures were shown to consist of cell-to-cell closely packed transmembrane channels
- Proteins, called connexins, purified from fractions of enriched gap junctions from different tissues differ
- Connexins are designated by their molecular mass
- Another system of nomenclature divides gap junction proteins into 2 categories, alpha and beta, according to sequence similarities at the nucleotide and amino acid levels
- For example, CX43 is designated alpha-1 gap junction protein, whereas CX32 and CX26 are called beta-1 and beta-2 gap junction proteins, respectively
- This nomenclature emphasizes that CX32 and CX26 are more homologous to each other than either of them is to CX43
- Connexins have four transmembrane, three intracellular, and two extracellular regions
- Different tissues express different connexins, though tissue specificities overlap, and a given tissue or cell can express several different connexins
- Developmental regulation of at least some of the connexin genes has been found
- Embryo implantation is regulated in part by temporally changing patterns of expression of connexins in the embryo and the maternal decidua.