NOTCH1 Monoclonal Antibody (mN1A), Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 41-350-0-Each-of-1 | In Stock | ₹ 44,500.00 |
41-350-0 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,500.00
GST (18%): ₹ 8,010.00
Total Price: ₹ 52,510.00
Antigen
NOTCH1
Classification
Monoclonal
Concentration
0.5 mg/mL
Formulation
PBS with 0.1% sodium azide; pH 7.4
Gene Accession No.
P46531, Q01705, Q07008
Gene Symbols
Notch1
Immunogen
Recombinant protein derived from the intracellular domain of mouse Notch1
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Bovine, Human, Mouse, Non-human Primate, Rat
Product Type
Antibody
Isotype
IgG1
Applications
Flow Cytometry, Western Blot
Clone
mN1A
Conjugate
Unconjugated
Gene
Notch1
Gene Alias
9930111A19Rik; AOS5; AOVD1; Drosophila Notch homolog 1 (controlling the the ectodermal and neural cell fate in Drosophila); hN1; lin-12; major type A protein; Mis6; Motch; Motch A; mT14; N1; neurogenic locus notch homolog protein 1; NEXT; NICD; NOTCH; notch 1; Notch 1 extracellular truncation; Notch 1 intracellular domain; Notch gene homolog 1; Notch homolog 1, translocation-associated; notch receptor 1; Notch1; p300; RP23-306D20.12; RP23-306D20.12-001; Tan1; Translocation-associated notch protein TAN-1; transmembrane receptor Notch1
Host Species
Mouse
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
18128, 25496, 4851, 767866
Content And Storage
-20°C
Form
Liquid
Related Products
Description
- This antibody is specific for the Notch1 (neurogenic locus notch homolog protein1, Motch A, mT14, p300) protein
- This antibody gives a band of ∽65 kDa on Western blot analysis using Notch1-IC OP transfected cells
- Western blot analysis using Jurkat cells expresses the target band at ∽110-120 kDa, with an additional band occasionally observed at ∽220kDa
- This antibody does not cross-react with Notch 2,3, and 4 as assessed by Western blot analysis
- The notch gene belongs to a family of epidermal growth factor (EGF) like homeotic genes, which encode transmembrane proteins with a variable number of cysteine-rich EGF-like repeats in the extracellular region
- Four notch genes have been described in mammals: Notch1, Notch2, Notch3 and Notch4(Int-3), which have been implicated in the differentiation of the nervous system and other structures
- The EGF-like proteins Delta and Serrate have been identified as ligands of Notch1
- Mature Notch proteins are heterodimeric receptors derived from the cleavage of Notch pre-proteins into an extracellular subunit (NEC) containing multiple EGF-like repeats and a transmembrane subunit including intracellular region (Ntm).