Phospho-VE-cadherin (Tyr658) Polyclonal Antibody, Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 44-114-4G-Each-of-1 | In Stock | ₹ 39,694.00 |
44-114-4G - Each of 1
In Stock
Quantity
1
Base Price: ₹ 39,694.00
GST (18%): ₹ 7,144.92
Total Price: ₹ 46,838.92
Antigen
Phospho-VE-cadherin (Tyr658)
Classification
Polyclonal
Formulation
Dulbecco's PBS with 1mg/mL BSA and 0.05% sodium azide; pH 7.3
Gene Accession No.
P33151, P55284
Gene Symbols
CDH5
Immunogen
The antiserum was produced against a chemically synthesized phosphopeptide derived from the region of human VE-cadherin that contains tyrosine 658. This sequence is conserved in chicken, chimpanzee, cow, dog, mouse, pig, and rat.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Applications
Western Blot
Conjugate
Unconjugated
Gene
CDH5
Gene Alias
7B4; 7B4 antigen; 7B4/cadherin-5; AA408225; cadherin 5; cadherin 5, type 2 (vascular endothelium); cadherin 5, type 2, VE-cadherin (vascular endothelium); cadherin 5, type 2, VE-cadherin (vascular epithelium); cadherin-5; cadherin-5; cd144 antigen; VE cadherin; Cd144; cd144 antigen; CDH5; cell-cell adhesion protein; endothelial-specific cadherin; vascular endothelial cadherin; vascular endothelial cadherin precursor; Vec; VEcad; VE-Cad; VE-cadherin; VECD
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
1003, 12562
Content And Storage
-20°C
Form
Liquid
Related Products
Description
- This antibody has been negatively preadsorbed using a non-phosphopeptide corresponding to the site of phosphorylation to remove antibody that is reactive with non-phosphorylated VE-cadherin
- The final product is generated by affinity chromatography using an VE-cadherin-derived peptide that is phosphorylated at tyrosine 658
- Positive controls used with this antibody in western blotting were HUVEC +/- VEGF
- VE-cadherin is a member of the cadherin superfamily that is located in a six-cadherin cluster in a region on the long arm of chromosome 16 and is involved in loss of heterozygosity events in breast and prostate cancer
- VE-cadherin protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail
- Functioning as a classic cadherin by imparting to cells the ability to adhere in a homophilic manner, VE-cadherin may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions
- An alternative splice variant has been described but the full length sequence of VE-cadherin has not been determined.