44-281-G

Phospho-c-Fos (Thr325) Polyclonal Antibody, Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each of 1 44-281-G-Each-of-1 In Stock ₹ 44,500.00

44-281-G - Each of 1

₹ 44,500.00

In Stock

Quantity

1

Base Price: ₹ 44,500.00

GST (18%): ₹ 8,010.00

Total Price: ₹ 52,510.00

Antigen

Phospho-c-Fos (Thr325)

Classification

Polyclonal

Formulation

Dulbecco's PBS with 1mg/mL BSA and 0.05% sodium azide; pH 7.3

Gene Accession No.

P01100

Gene Symbols

FOS

Immunogen

The antiserum was produced against a chemically synthesized phosphopeptide derived from the region of human c-Fos that contains threonine 325. The sequence is conserved in human, mouse and rat.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

ChIP Assay, Immunocytochemistry, Western Blot

Conjugate

Unconjugated

Gene

FOS

Gene Alias

activator protein 1; AP-1; cellular oncogene c-fos; cellular oncogene fos; cFos; C-FOS; c-fos oncogene; c-fos protooncogene protein; D12Rfj1; FBJ murine osteosarcoma viral (v-fos) oncogene homolog (oncogene FOS); FBJ murine osteosarcoma viral oncogene homolog; FBJ murine osteosarcoma viral oncogene homolog B; FBJ osteosarcoma oncogene; FBJ osteosarcoma oncogene B; FBJ osteosarcoma viral oncogene isoform deltaFosb-2; FOS; Fos proto-oncogene, AP-1 trancription factor subunit; Fos proto-oncogene, AP-1 transcription factor subunit; Fosb; FosB proto-oncogene, AP-1 transcription factor subunit; fra-2; G0/G1 switch regulatory protein 7; G0S7; I79_009428; p55; protein fosB; proto-oncogene cFOS; proto-oncogene c-Fos; proto-oncogene protein c-fos; v-fos FBJ murine osteosarcoma viral oncogene homolog

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

2353

Content And Storage

-20°C

Form

Liquid

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Description

  • FBJ murine osteosarcoma viral oncogene homolog is commonly known as Cellular protooncogene Fos (c-Fos)
  • It belongs to the fos transcription factor family and is encoded by the C-FOS gene located on chromosome 14
  • c-Fos heterodimerizes with c-Jun to form the Activator Protein -1 (AP-1) transcription factor which regulates transcription of several genes that play an important role in cellular signal transduction, cell proliferation and differentiation
  • c-Fos has been shown to be phosphorylated by various stimuli including growth factors and insulin at atleast seven different sites
  • The best known upstream kinase for phosphorylation at Threonine 232 is ERK MAPK which regulates localization of c-Fos to the nucleus and is thus important for c-Fos induced transcriptional activity.