BID p15 Polyclonal Antibody, Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 44-436-G-Each-of-1 | In Stock | ₹ 38,270.00 |
44-436-G - Each of 1
In Stock
Quantity
1
Base Price: ₹ 38,270.00
GST (18%): ₹ 6,888.60
Total Price: ₹ 45,158.60
Antigen
BID p15
Classification
Polyclonal
Formulation
Dulbecco's PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide; pH 7.3
Gene Accession No.
P55957, P70444
Gene Symbols
BID
Immunogen
The antiserum was produced against a chemically synthesized peptide derived from the 15 kDa caspase-8 cleavage product of mouse BID.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Applications
Immunocytochemistry, Western Blot
Conjugate
Unconjugated
Gene
BID
Gene Alias
2700049M22Rik; AI875481; apoptic d; apoptic death agonist; AU022477; BH3 interacting domain death agonist; BH3-interacting domain death agonist; BH3-interacting domain death agonist p11; BH3-interacting domain death agonist p13; BH3-interacting domain death agonist p15; BID; BID isoform ES(1b); BID isoform L(2); BID isoform Si6; desmocollin type 4; FP497; HGNC:1050; Human BID coding sequence; MGC15319; MGC42355; OTTHUMP00000196197; p11 BID; p13 BID; p15 BID; p22 BID
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
12122, 637
Content And Storage
-20°C
Form
Liquid
Related Products
Description
- BID is a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2
- Bid is a member of the BCL-2 family of cell death regulators
- BID is a mediator of mitochondrial damage induced by caspase-8 (CASP8); CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release
- BID is also a pro-apoptotic member of the Bcl 2 family
- BID usually exists in an inactive form in the cytosolic fraction of living cells and becomes cleaved and activated by caspase 8 in response to TNF alpha or Fas ligand
- Once BID is cleaved, the C-terminal 15 kDa fragment of BID (p15) translocates onto mitochondria and is sufficient to trigger cytochrome c release, resulting in cell apoptosis
- BID serves as a direct molecular link between caspase 8 activation and mitochondrial death machinery.