44-528-G

Phospho-eIF4E (Ser209) Polyclonal Antibody, Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each 44-528-G-Each In Stock ₹ 43,222.85

44-528-G - Each

₹ 43,222.85

In Stock

Quantity

1

Base Price: ₹ 43,222.85

GST (18%): ₹ 7,780.113

Total Price: ₹ 51,002.963

Antigen

Phospho-eIF4E (Ser209)

Classification

Polyclonal

Formulation

Dulbecco's PBS with 1mg/mL BSA and 0.05% sodium azide; pH 7.3

Gene Accession No.

P06730, P29338, P63073, P63074

Gene Symbols

Eif4e

Immunogen

The antiserum was produced against a chemically synthesized phosphopeptide derived from the region of human eIF4E that contains serine 209. The sequence is conserved in mouse, rat and rabbit.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rabbit, Rat

Product Type

Antibody

Isotype

IgG

Applications

Immunocytochemistry, Immunoprecipitation, Immunoprecipitation, Western Blot

Conjugate

Unconjugated

Gene

Eif4e

Gene Alias

AUTS19; CBP; EG668879; EIF4E; EIF-4E; EIF4E1; EIF4EL1; Eif4e-ps; EIF4F; eIF-4F 25 kDa subunit; eukaryotic translation initiation factor 4E; eukaryotic translation initiation factor 4E-like 1; eukaryotic translation initiation factor 4E-like protein; eukaryotic translation initiation factor 4-like protein; If4e; MGC111573; mRNA cap-binding protein; OTTHUMP00000219703; OTTHUMP00000219704; OTTHUMP00000219705; translation initiation factor eIF-4E

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

100009338, 117045, 13684, 1977

Content And Storage

-20°C

Form

Liquid

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Description

  • eIF4E is involved in several cellular processes including enhanced translational efficiency, splicing, mRNA stability, and RNA nuclear export
  • All eukaryotic cellular mRNAs are blocked at their 5-prime ends with the 7-methylguanosine cap structure, m7GpppX (where X is any nucleotide)
  • EIF4E is a eukaryotic translation initiation factor involved in directing ribosomes to the cap structure of mRNAs
  • It is a 24-kD polypeptide that exists as both a free form and as part of a multiprotein complex termed EIF4F
  • The EIF4E polypeptide is the rate-limiting component of the eukaryotic translation apparatus and is involved in the mRNA-ribosome binding step of eukaryotic protein synthesis
  • The other subunits of EIF4F are a 50-kD polypeptide, termed EIF4A, that possesses ATPase and RNA helicase activities, and a 220-kD polypeptide, EIF4G.