4538187
Epredia™ Lab Vision™ Cadherin E Ab-4, Mouse Monoclonal Antibody
Obtain accurate, reproducible results in immunohistochemistry experiments with Epredia™ Cadherin E Ab-4, Mouse Monoclonal Antibody.
Manufacturer: Fischer Scientific
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Antigen
Cadherin E/E-Cadherin Ab-4
Applications
Immunohistochemistry (Paraffin)
Conjugate
Unconjugated
Regulatory Status
RUO
Target Species
Human
Isotype
IgG2a κ
Clone
NCH-38
Classification
Monoclonal
Host Species
Mouse
Research Discipline
Junction Protein
Immunogen
E-cadherin and GST recombinant protein
Primary or Secondary
Primary
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Description
- E-cadherin (uvomorulin, cell-CAM120/80) is a calcium-dependent cell adhesion molecule expressed predominately in epithelial tissues
- It plays an important role in the growth and development of cells via the mechanisms of control of tissue architecture and the maintenance of tissue integrity
- Numerous studies have demonstrated that reduction and/or loss of E-cadherin expression in carcinomas correlates positively with the potential of these tumors for invasion and metastasis
- Host Species: Mouse Clone: NCH-38 Isotype: IgG1/κ Species Reactivity: Human
- Others not known
- Epitope: Not determined Immunogen: E-cadherin and GST recombinant protein Molecular Weight: 120 kDa Positive Control: Breast CA Cellular Localization: Membrane Recommended for: Immunohistochemistry (Formalin/paraffin only) Note: USA: IVD; Int'l: IVD