4541099
Chromogranin A Ab-3 Mouse Monoclonal Antibody, Epredia™
Obtain accurate, reproducible results in immunohistochemistry experiments with Epredia™ Chromogranin A Ab-3, Mouse Monoclonal Antibody.
Manufacturer: Fischer Scientific
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Antigen
Chromogranin A Ab-3
Applications
Immunohistochemistry (Paraffin)
Conjugate
Unconjugated
Regulatory Status
RUO
Target Species
Human, Non-human Primate
Isotype
IgG1
Clone
LK2H10 + PHE5
Classification
Monoclonal
Host Species
Mouse
Research Discipline
Oncogenesis
Immunogen
Human pheochromocytoma
Primary or Secondary
Primary
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Description
- Chromogranin A (a protein of 439-amino acid which is encoded on chromosome 14) is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets
- It is an excellent marker for carcinoid tumors, pheo-chromocytomas, paragangliomas, and other neuro-endocrine tumors
- Coexpression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms
- Ab-3 cocktail is especially designed for sensitive detection of Chromogranin A in formalin-fixed, paraffin-embedded tissues
- Host Species: Mouse Clone: LK2H10 + PHE5 Isotype: IgG1 + IgG1 Species Reactivity: Human and Monkey
- Others not known
- Immunogen: Human pheochromocytoma Molecular Weight: 68-75 kDa Positive Control: Pancreas Cellular Localization: Cytoplasmic in endocrine cells Recommended for: Immunohistochemistry (Formalin/paraffin) Note: USA: RUO; Int'l: RUO