4547022
Epredia™ Lab Vision™ CD141/Thrombomodulin Ab-1, Mouse Monoclonal Antibody
Optimize immunohistochemical staining of formalin-fixed tissue using Epredia™ CD141/Thrombomodulin Ab-1, Mouse Monoclonal Antibody.
Manufacturer: Fischer Scientific
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Antigen
CD141
Applications
Immunohistochemistry (Paraffin)
Conjugate
Unconjugated
Regulatory Status
RUO
Target Species
Human, Rat
Isotype
IgG2a κ
Clone
141C01; same as 1009
Classification
Monoclonal
Host Species
Mouse
Research Discipline
Hematopoietic
Immunogen
Recombinant protein encoding the six repeated EGF domains of human thrombomodulin
Primary or Secondary
Primary
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Description
- Thrombomodulin (TM) is also known as Fetomodulin (FM), endothelial anticoagulant protein, or glycoprotein P112
- Thrombomodulin contains six repeated domains homologous with epidermal growth factor (EGF) and an amino terminal domain homologous to lectin-like protein
- Through its accelerated activation of protein C, synthesis of TM is one of several mechanisms important in maintaining thrombo-resistance and thus reducing clot formation on the surface of the endothelial cells
- Immunohistochemical staining of formalin-fixed tissue for TM has been used for the study of a variety of vascular tumors, meningiomas and choriocarcinomas
- Host Species: Mouse Clone: 141C01; same as 1009 Isotype: IgG1/κ Species Reactivity: Human and Rat
- Others not known
- Epitope: EGF domain Immunogen: Recombinant protein encoding the six repeated EGF domains of human thrombomodulin Molecular Weight: 75kDa Positive Control: Mesothelioma Cellular Localization: Membrane Recommended for: Immunohistochemistry (Formalin/paraffin) Note: USA: RUO; Int'l: RUO