4547911

HER-2/c-erbB-2/neu Ab-17 Mouse Monoclonal Antibody, Epredia™

Recommended for Immunohistochemistry (Formalin/paraffin), Western Blotting and Immunoprecipitation (For cytoplasmic), Epredia™ HER-2/c-erbB-2/neu Ab-17, Mouse Monoclonal Antibody provides accurate, reproducible results..

Manufacturer: Fischer Scientific

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Antigen

HER-2/c-erbB-2/neu Ab-17

Applications

Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Conjugate

Unconjugated

Regulatory Status

ASR, IVD

Target Species

Human, Rat

Isotype

IgG1

Clone

e2-4001 + 3B5

Classification

Monoclonal

Host Species

Mouse

Research Discipline

EGFR Family

Immunogen

Cytoplasmic domain of recombinant human c-erbB-2/HER-2 oncoprotein (e2-4001) and a synthetic peptide from the C-terminus of human c-erbB-2 protein (3B5)

Primary or Secondary

Primary

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Description

  • c-erbB-2 is a receptor tyrosine kinase of the c-erbB family
  • Approximately 25% of primary breast and ovarian tumors were found to overexpress the protein Host Species: Mouse Clone: e2-4001 + 3B5 Isotype: IgG1 + IgG1 Species Reactivity: Human and Rat
  • Others not known
  • Epitope: Cytoplasmic Immunogen: Cytoplasmic domain of recombinant human HER-2/c-erbB-2 oncoprotein (e2-4001) and a synthetic peptide from the C-terminus of human HER-2 protein (3B5) Molecular Weight: 185kDa Positive Control: LS174T cells, or Breast CA Cellular Localization: Membrane Recommended for: Immunohistochemistry (Formalin/paraffin) Western Blotting Immunoprecipitation (For cytoplasmic)