4549793
Insulin Receptor (α-subunit) Ab-2 Mouse Monoclonal Antibody, Epredia™
Epredia™ Insulin Receptor (α-Subunit) Ab-2, Mouse Monoclonal Antibody provides accurate, reproducible results.
Manufacturer: Fischer Scientific
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Antigen
Insulin Receptor (alpha-Subunit) Ab-2
Applications
Immunohistochemistry (Paraffin)
Host Species
Mouse
Research Discipline
Steroids Hormones and Growth Factors
Immunogen
IM-9 lymphocytes followed by IR
Primary or Secondary
Primary
Clone
83-7
Classification
Monoclonal
Regulatory Status
RUO
Target Species
Bovine, Human, Porcine, Rabbit, Sheep
Isotype
IgG2a κ
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Description
- The human insulin receptor is a heterotetrameric membrane glycoprotein consisting of disulfide-linked subunits in a Β-α-α-Β configuration
- The Β-subunit (95kDa) possesses a single transmembrane domain, whereas the α-subunit (135kDa) is completely extracellular
- Host Species: Mouse Clone: 83-7 Isotype: IgG1/κ Species Reactivity: Human, Cow, Pig, Sheep and Rabbit
- Does not react with mouse and rat
- Epitope: Exon 3 Immunogen: IM-9 lymphocytes followed by IR Molecular Weight: 135kDa Positive Control: IM-9 lymphocyte cells, Placenta Cellular Localization: Cell membrane Recommended for: Immunohistochemistry (Formalin/paraffin) ELISA Flow Cytometry Insulin-like Agonist Does Not Significantly Inhibit Insulin Binding Tyrosine Kinase Assay (Ab-mediated capture on microplates) Note: USA: RUO; Int'l: RUO