4552442
Epredia™ Lab Vision™ NY-BR-1 Mouse Monoclonal Antibody
Take advantage of a quality product that delivers accurate results with the Epredia™ NY-BR-1, Mouse Monoclonal Antibody.
Manufacturer: Fischer Scientific
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Antigen
NY-BR-1
Applications
Immunohistochemistry
Host Species
Mouse
Primary or Secondary
Primary
Clone
NY-BR-1 No.2
Conjugate
Unconjugated
Immunogen
a 77 aa peptide from human NYBR-1 protein
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Description
- NY-BR-1 is a novel differentiation marker predominantly expressed in normal breast and breast cancer
- It has been shown by Immunohistochemistry (IHC) that NY-BR-1 was present solely in ductal epithelium of normal breast tissue
- Invasive carcinoma of the breast and carcinoma in situ were positive for NY-BR-1, whereas most other tumors and normal tissues are negative, with the exceptions of one-third of sweat gland carcinomas and around two percent of prostate carcinoma
- NY-BR-1 is reported to express more frequently in estrogen-positive and lymph node-negative primary carcinomas, and more commonly in grade 1 than in grade 2 or grade 3
- In a study by Varga et al (2006) forty-nine percent of lymph node metastasis were shown to be positive
- Host Species: Mouse Clone: NY-BR-1No
- 2 Isotype: IgG1/κ Species Reactivity: Human
- Others not tested
- Epitope: Not determined Immunogen: a 77 aa peptide from human NYBR-1 protein Molecular Weight: 150-160kDa Positive Control: Breast carcinoma Cellular Localization: Predominantly cytoplasmic and occasional nuclear Recommended for: Immunohistochemistry (Formalin/paraffin)