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46-071-942

CD71 (Transferrin Receptor) Monoclonal Antibody (OKT9 (OKT-9)), PerCP-eFluor™ 710, eBioscience™, Invitrogen™

Manufacturer: eBioscience

Select a Size

Pack Size SKU Availability Price
Each of 1 46-071-942-Each-of-1 In Stock ₹ 34,621.00

46-071-942 - Each of 1

₹ 34,621.00

In Stock

Quantity

1

Base Price: ₹ 34,621.00

GST (18%): ₹ 6,231.78

Total Price: ₹ 40,852.78

Antigen

CD71 (Transferrin Receptor)

Classification

Monoclonal

Concentration

5 μL/Test

Formulation

PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.

P02786

Gene Symbols

TFRC

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

7037

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Form

Liquid

Applications

Flow Cytometry

Clone

OKT9 (OKT-9)

Conjugate

PerCP-eFluor 710

Gene

TFRC

Gene Alias

2610028K12Rik; AI195355; AI426448; AU015758; CD antigen CD71; CD71; chicken transferrin receptor; E430033M20Rik; I79_000642; IMD46; mammary tumor virus receptor 1; Mtvr1; Mtvr-1; p90; sTfR; T9; TfR; tfR1; TFR2; TFRC; TR; transferrin receptor; transferrin receptor (p90, CD71); transferrin receptor 2; transferrin receptor protein 1; Transferrin receptor protein 1, serum form; Trfr

Host Species

Mouse

Quantity

100 Tests

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1 κ

Description

  • Description: The OKT9 monoclonal antibody reacts with human CD71, a 170-180 kDa type II transmembrane protein
  • CD71, the transferrin receptor, exists as a homodimer on the cell surface and is essential for cellular growth
  • CD71 is expressed by immature proliferating cells and at low levels on resting mature lymphocytes
  • Antigen or mitogen stimulation of T and B cells upregulates the expression of CD71
  • Applications Reported: This OKT9 (OKT-9) antibody has been reported for use in flow cytometric analysis
  • Applications Tested: This OKT9 (OKT-9) antibody has been pre-diluted and tested by flow cytometric analysis of stimulated normal human peripheral blood cells
  • This may be used at 5 μL (0.5 μg) per test
  • A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
  • Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
  • PerCP-eFluor 710 emits at 710 nm and is excited with the blue laser (488 nm); it can be used in place of PerCP-Cyanine5.5
  • We recommend using a 710/50 bandpass filter, however, the 695/40 bandpass filter is an acceptable alternative
  • Please make sure that your instrument is capable of detecting this fluorochrome
  • Light sensitivity: This tandem dye is sensitive to photo-induced oxidation
  • Please protect this vial and stained samples from light
  • Fixation: Samples can be stored in IC Fixation Buffer (Product No
  • Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes
  • Endosomal acidification leads to iron release
  • The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor
  • Transferrin receptor is necessary for development of erythrocytes and the nervous system
  • Serum transferrin receptor (sTfR) is used as a means of detecting erythropoietin (EPO) misuse by athletes and as a diagnostic test for anemias resulting from a number of conditions including rheumatoid arthritis, pregnancy, irritable bowel syndrome and in HIV patients.