4697054

CD5 Mouse anti-Human, Brilliant Violet 510, Clone: UCHT2, BD

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

CD5

Applications

Flow Cytometry

Conjugate

Brilliant Violet 510

Regulatory Status

RUO

Formulation

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Isotype

IgG1 κ

Purification Method

Affinity Purified

Description

CD5 antigen (p56-62); T1; Tp67; LEU1; Lymphocyte antigen T1/Leu-1

Clone

UCHT2

Classification

Monoclonal

Host Species

Mouse

Target Species

Human

Immunogen

Human T cells

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Description

  • The UCHT2 monoclonal antibody specifically binds to CD5
  • CD5 is a 67 kDa single-chain, type 1 transmembrane glycoprotein expressed on most thymocytes, the majority of peripheral T lymphocytes and a subpopulation of B cells
  • CD72 has been shown to be the natural ligand for CD5
  • CD5+ B cells produce polyreactive antibodies (mostly IgM)
  • The antibody was conjugated to BD Horizon™ BV510 which is part of the BD Horizon™ Brilliant Violet™ family of dyes
  • With an Ex Max of 405-nm and Em Max at 510-nm, BD Horizon™ BV510 can be excited by the violet laser and detected in the BD Horizon™ V500 (525/50-nm) filter set
  • BD Horizon™ BV510 conjugates are useful for the detection of dim markers off the violet laser.