47-105-741
CD105 (Endoglin) Monoclonal Antibody (SN6), APC-eFluor™ 780, eBioscience™, Invitrogen™
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 47-105-741-Each-of-1 | In Stock | ₹ 14,507.00 |
47-105-741 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 14,507.00
GST (18%): ₹ 2,611.26
Total Price: ₹ 17,118.26
Antigen
CD105 (Endoglin)
Classification
Monoclonal
Concentration
5 μL/Test
Formulation
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.
P17813
Gene Symbols
ENG
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
2022
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Applications
Flow Cytometry
Clone
SN6
Conjugate
APC-eFluor 780
Gene
ENG
Gene Alias
AI528660; AI662476; CD105; CD105 antigen; cell surface MJ7/18 antigen; Edg; END; Endo; Endoglin; endoglin (Osler-Rendu-Weber syndrome 1); Eng; HHT1; ORW; ORW1; S-endoglin; transmembrane glycoprotein
Host Species
Mouse
Quantity
25 Tests
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1 κ
Related Products
Description
- Description: The SN6 monoclonal antibody reacts with human CD105, also known as Endoglin
- CD105, an approximately 90 kDa disulfide-linked homodimer is expressed by vascular endothelial cells and some bone marrow cells and activated macrophages
- It is suggested that CD105 functions in adhesion and embryonic angiogenesis
- Applications Reported: This SN6 antibody has been reported for use in flow cytometric analysis
- Applications Tested: This SN6 antibody has been pre-diluted and tested by flow cytometric analysis of U937 cell line
- This may be used at 5 μL (0.5 μg) per test
- A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
- Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
- APC-eFluor 780 emits at 780 nm and is excited with the Red laser (633-647 nm)
- Please make sure that your instrument is capable of detecting this fluorochrome
- Light sensitivity: This tandem dye is sensitive to photo-induced oxidation
- Please protect this vial and stained samples from light
- Fixation: Samples can be stored in IC Fixation Buffer (Product No
- 00-8222-49) (100 μL of cell sample + 100 μL of IC Fixation Buffer) or 1-step Fix/Lyse Solution (Product No
- 00-5333-57) for up to 3 days in the dark at 4°C with minimal impact on brightness and FRET efficiency/compensation
- CD105 or Endoglin is a Type I transmembrane protein, which is highly expressed on human vascular endothelial cells
- It exists on an O- and N-glycosylated homodimer
- Up regulation of endoglin expression has been demonstrated in tumor vasculature and proliferating cells, suggesting that it is a proliferation associated endothelial marker
- CD105 binds to TGF beta 1 and 3 with high affinity but not to TGF beta 2.