4840461

CD56 Mouse anti-Human, BB515, Clone: B159, BD

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

CD56

Applications

Flow Cytometry

Conjugate

Brilliant Blue 515 (BB515)

Regulatory Status

RUO

Immunogen

Human NK Cells

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Clone

B159

Classification

Monoclonal

Host Species

Mouse

Target Species

Human

Isotype

IgG1 κ

Purification Method

Affinity Purified

Description

NCAM1; NCAM-1; Neural cell adhesion molecule 1; NCAM; NKH1; MSK39

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Description

  • The B159 monoclonal antibody specifically binds to CD56
  • CD56 is a heavily glycosylated adhesion protein that is present on a subpopulation of peripheral blood large granular lymphocytes that demonstrate natural killer activity
  • CD56 is also expressed on a subset of T cells but is not expressed on myeloid cells, erythrocytes or B cells
  • This antigen is a pan-NK-cell marker
  • CD56 is virtually identical to an isoform of the neural cell adhesion molecule (NCAM), a structure mediating homotypic and heterotypic cell-cell interactions
  • The antibody was conjugated to BD Horizon™ BB515 which was developed exclusively by BD Biosciences
  • With an excitation max of 490nm and an emission max of 515nm, BD Horizon BB515 can be excited by the 488nm laser and detected in a standard FITC set (e.g., 530/30-nm filter)
  • This dye provides a much brighter alternative to FITC with less spillover into the PE detector.