50-0M1-28500U
IL-10 Monoclonal Antibody, PeproTech®, Invitrogen™
Manufacturer: Pepro Tech Inc
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-0M1-28500U-Each-of-1 | In Stock | ₹ 16,109.00 |
50-0M1-28500U - Each of 1
In Stock
Quantity
1
Base Price: ₹ 16,109.00
GST (18%): ₹ 2,899.62
Total Price: ₹ 19,008.62
Antigen
IL-10
Classification
Monoclonal
Formulation
PBS with no preservative
Gene Accession No.
P18893
Gene Symbols
IL10
Immunogen
E.coli-derived Recombinant Murine IL-10
Quantity
500 μg
Primary or Secondary
Primary
Target Species
Mouse
Product Type
Antibody
Applications
ELISA, Western Blot
Conjugate
Unconjugated
Gene
IL10
Gene Alias
CSIF; cytokine; Cytokine synthesis inhibitory factor; GVHDS; H-IL-10; il 10; IL10; IL-10; IL-10 precursor; IL10A; IL10X; ILN; Interleukin; interleukin 10; Interleukin10; interleukin-10; MGC126450; MGC126451; RP11-262N9.1; T-cell growth inhibitory factor; TGIF
Host Species
Rat
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
16153
Content And Storage
-20°C
Form
Lyophilized
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Description
- AA Sequence of recombinant protein: MSRGQYSRED NNCTHFPVGQ SHMLLELRTA FSQVKTFFQT KDQLDNILLT DSLMQDFKGY LGCQALSEMI QFYLVEVMPQ AEKHGPEIKE HLNSLGQKLK TLRMRLRRCH RFLPCENKSK AVEQVKSDFN KLEDQGVYKA MNEFDIFINC IEAYMMIKMK S
- Preparation: Produced in Sprague Dawley rats immunized with highly pure Recombinant Murine IL-10
- Anti-Murine IL-10-specific antibody was purified from cell culture by Protein G affinity chromatography
- IL-10 encodes a protein that acts as a cytokine and is primarily produced by monocytes, with some production by lymphocytes
- This cytokine has various effects on immunoregulation and inflammation, including down-regulating the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages
- It also enhances B cell survival, proliferation, and antibody production
- Additionally, IL-10 can block NF-kappa B activity and is involved in the regulation of the JAK-STAT signaling pathway
- Knockout studies in mice have suggested that this cytokine is an essential immunoregulator in the intestinal tract
- Mutations in this gene have been associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis
- Diseases associated with IL10 include Graft-Versus-Host Disease and Human Immunodeficiency Virus Type 1.