50-107-13
CD201 (EPCR) Monoclonal Antibody (eBio1560 (1560)), PE, eBioscience™, Invitrogen™
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-107-13-Each-of-1 | In Stock | ₹ 34,176.00 |
50-107-13 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 34,176.00
GST (18%): ₹ 6,151.68
Total Price: ₹ 40,327.68
Antigen
CD201 (EPCR)
Classification
Monoclonal
Concentration
0.2 mg/mL
Formulation
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.
Q64695
Gene Symbols
Procr
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
19124
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Applications
Flow Cytometry
Clone
eBio1560 (1560)
Conjugate
PE
Gene
Procr
Gene Alias
Activated protein C receptor; AI325044; APC receptor; bA42O4.2; CCCA; CCD41; CD antigen CD201; CD201; CD201 antigen; cell cycle, centrosome-associated protein; centrocyclin; Centrosomal protein CCD41; endothelial cell protein C receptor; Endothelial protein C receptor; Epcr; PROCR; protein C receptor; protein C receptor, endothelial
Host Species
Rat
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Mouse
Product Type
Antibody
Isotype
IgG2b κ
Related Products
Description
- Description: The eBio1560 monoclonal antibody reacts with mouse Endothelial Protein C Receptor (EPCR, CD201), a 25 kDa Type 1 transmembrane protein expressed on endothelial cells
- EPCR exhibits sequence and structural homology with the MHC class I/CD1 family of proteins
- EPCR is a ligand for Protein C and plays an important role in augmenting Protein C activation by the thrombin-thrombomodulin complex and in regulating blood coagulation and inflammation
- Deletion of EPCR results in embryonic lethality, at least partically due to placental thrombosis
- Recently, it was demonstrated that EPCR expression identified cells in the bone marrow that are capable of hematopoietic reconstitution activity comparable to hematopoietic stem cells isolated with conventional methods
- The eBio1560 monoclonal antibody can be used for the detection of these hematopoietic stem cells, however the eBiomRCR-16 monoclonal antibody should only be used for the detection of CD201 on endothelial cells
- Applications Reported: This eBio1560 (1560) antibody has been reported for use in flow cytometric analysis
- Applications Tested: This eBio1560 (1560) antibody has been tested by flow cytometric analysis of the bEnd.3 cell line
- This can be used at less than or equal to 1 μg per test
- A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
- The protein encoded by this gene is a receptor for activated protein C, a serine protease activated by and involved in the blood coagulation pathway
- The encoded protein is an N-glycosylated type I membrane protein that enhances the activation of protein C
- Mutations in this gene have been associated with venous thromboembolism and myocardial infarction, as well as with late fetal loss during pregnancy.