Galectin 3 Monoclonal Antibody (eBioM3/38 (M3/38)), PE, eBioscience™, Invitrogen™
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each | 50-108-17-Each | In Stock | ₹ 25,689.85 |
50-108-17 - Each
In Stock
Quantity
1
Base Price: ₹ 25,689.85
GST (18%): ₹ 4,624.173
Total Price: ₹ 30,314.023
Antigen
Galectin 3
Classification
Monoclonal
Concentration
0.2 mg/mL
Formulation
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.
P16110, P17931
Gene Symbols
LGALS3
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
16854, 3958
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Applications
Flow Cytometry
Clone
eBioM3/38 (M3/38)
Conjugate
PE
Gene
LGALS3
Gene Alias
35 kDa lectin; advanced glycation end-product receptor 3; AGE-R3; beta-galactosides-binding lectin; carbohydrate-binding protein 35; CBP 35; CBP30; CBP-30; CBP35; epsilon BP; gal3; gal-3; galactose-specific lectin 3; Galactoside-binding protein; GALBP; galectin 3; Galectin3; galectin-3; GALIG; GBP; IgE binding protein; igE-binding protein; L-29; L31; L-31; L-34; L-34 galactoside-binding lectin; Laminin-binding protein; lectin galactoside-binding soluble 3; lectin galactoside-binding soluble 3 protein; lectin L-29; lectin, galactose binding, soluble 3; lectin, galactoside binding soluble 3; lectin, galactoside-binding, soluble, 3; lectin, galactoside-binding, soluble, 3 (galectin 3); LGALS2; Lgals3; MAC2; Mac-2; Mac-2 antigen
Host Species
Rat
Quantity
200 μg
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG2a κ
Related Products
Description
- Description: The eBioM3/38 antibody reacts with mouse Galectin-3 (Mac-2)
- Galectins are a family of animal lectins which appear to exhibit a variety of biological functions
- Galectin 3 (aka LGALS3, galactose-specific soluble lectin 3, Mac-2, L-29) is one of the more extensively studied members of this family and is a 30 kDa beta-galactoside-binding protein
- Due to a C-terminal carbohydrate binding site, Galectin 3 is capable of binding IgE and mammalian cell surfaces only when homodimerized or homo-oligomerized
- Galectin 3 is normally distributed in epithelia of many organs and various inflammatory cells, including macrophages, as well as dendritic cells and Kupffer cells
- The expression of this lectin is up-regulated during inflammation, cell proliferation, cell differentiation and through trans-activation by viral proteins
- This monoclonal antibody eBioM3/38 crossreacts to human Galectin-3 (LGALS3)
- Applications Reported: This eBioM3/38 (M3/38) antibody has been reported for use in flow cytometric analysis
- Applications Tested: This eBioM3/38 (M3/38) antibody has been tested by flow cytometric analysis of mouse thioglycolate-elicited peritoneal macrophages
- This can be used at less than or equal to 0.06 μg per test
- A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
- Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
- Galactose-specific lectin which binds IgE
- May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration
- Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis
- In the nucleus: acts as a pre-mRNA splicing factor
- Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells.