50-108-98
Embigin Monoclonal Antibody (G7.43.1), PE, eBioscience™, Invitrogen™
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each | 50-108-98-Each | In Stock | ₹ 13,140.85 |
50-108-98 - Each
In Stock
Quantity
1
Base Price: ₹ 13,140.85
GST (18%): ₹ 2,365.353
Total Price: ₹ 15,506.203
Antigen
Embigin
Classification
Monoclonal
Concentration
0.2 mg/mL
Formulation
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.
P21995
Gene Symbols
EMB
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
13723
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Applications
Flow Cytometry
Clone
G7.43.1
Conjugate
PE
Gene
EMB
Gene Alias
AL022799; EMB; Embigin; embigin homolog; glycoprotein 70; Gp70; Teratocarcinoma glycoprotein Gp-70
Host Species
Rat
Quantity
25 μg
Primary or Secondary
Primary
Target Species
Mouse
Product Type
Antibody
Isotype
IgG2b κ
Related Products
Description
- Description: This G7.43.1 monoclonal antibody reacts with mouse embigin (gp70), a single transmembrane glycoprotein that is a member of the Ig superfamily similar to basigin and EMMPRIN
- It contains two Ig domains thought to be involved in cellular adhesion and tissue remodeling
- Expression of embigin is high before day 10 in fetal development
- In the adult it is expressed on myeloid cells and T cells but not B cells
- During hematopoeisis, embigin is expressed on HSCs and CLPs (common lymphoid progenitors) but absent on pro- and pre-B cells
- In recent studies Pax 5 has been shown to repress embigin expression
- Applications Reported: This G7.43.1 antibody has been reported for use in flow cytometric analysis
- Applications Tested: This G7.43.1 antibody has been tested by flow cytometric analysis of mouse splenocytes
- This can be used at less than or equal to 1 μg per test
- A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
- Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
- It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest
- Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser
- Filtration: 0.2 μm post-manufacturing filtered
- Embigin is a 327 amino acid regulatory protein belonging to the immunoglobulin superfamily class of CAMs, and has two Ig-like (immunoglobulin-like) V- type domains
- In situ hybridization analysis shows that Embigin has specific carbohydrate epitopes and plays an important role in early postimplantation embryogenesis
- A highly glycosylated transmembrane glycoprotein, Embigin acts as a regulator of cell/ECM interactions during development and homeostasis of normal adult tissues
- Transfection studies suggest its role in promotion of integrin-mediated cell-substratum adhesion
- Widely expressed in most of the tissues and embryonal carcinoma cells, prostate and mammary cancer cell lines, it may also help in the classification of human carcinomas.