CD268 (BAFF Receptor) Monoclonal Antibody (8A7), FITC, eBioscience™, Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-112-2172-Each-of-1 | In Stock | ₹ 28,213.00 |
50-112-2172 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 28,213.00
GST (18%): ₹ 5,078.34
Total Price: ₹ 33,291.34
Antigen
CD268 (BAFF Receptor)
Classification
Monoclonal
Concentration
5 μL/Test
Formulation
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.
Q96RJ3
Gene Symbols
TNFRSF13C
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
115650
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Applications
Flow Cytometry
Clone
8A7
Conjugate
FITC
Gene
TNFRSF13C
Gene Alias
2010006P15Rik; B cell-activating factor receptor; BAFF receptor; BAFFR; BAFF-R; B-cell maturation defect; B-cell maturation defect 1; B-cell-activating factor receptor; Bcmd; Bcmd1; Bcmd-1; BLyS receptor 3; BR3; BROMIX; CD268; CVID4; Lvis22; prolixin; RGD1560810; TNF receptor superfamily member 13C; Tnfrsf13c; Tumor necrosis factor receptor superfamily member 13C; tumor necrosis factor receptor superfamily, member 13C
Host Species
Mouse
Quantity
100 Tests
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG2a κ
Related Products
Description
- Description: The 8A7 monoclonal antibody reacts with the human BAFF receptor, also known as B lymphocyte stimulator (BLyS protein) receptor, which is expressed on B cells
- The ligand for this receptor, BAFF (B cell-activating factor of the TNF family) is a B cell survival factor and regulates CD21/35 and CD23 expression
- Interaction of this ligand with its receptor causes elevated CD21/35 and CD23 expression, whereas receptor blockade has been shown to down-modulate expression
- Applications Reported: The 8A7 antibody has been reported for use in flow cytometric analysis
- Applications Tested: The 8A7 antibody has been pre-titrated and tested by flow cytometric analysis of normal human peripheral blood cells
- This can be used at 5 μL (0.125 μg) per test
- A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
- Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
- Excitation: 488 nm; Emission: 520 nm; Laser: Blue Laser
- Filtration: 0.2 μm post-manufacturing filtered
- Tumor necrosis factor receptor superfamily member 13C (TNFRSF13C), also known as BAFFR, is a protein in humans is encoded by the TNFRSF13C gene
- The BAFFR gene is mapped to chromosome 22q13
- 1-q13
- 31
- It has got 184 amino acid transmembrane protein which is 56% identical to the mouse protein
- B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population
- BAFF plays a crucial role in B cell development and can function through receptors other than BCMA.