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50-112-3163

iNOS Monoclonal Antibody (CXNFT), APC, eBioscience™, Invitrogen™

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 50-112-3163-Each-of-1 In Stock ₹ 37,113.00

50-112-3163 - Each of 1

₹ 37,113.00

In Stock

Quantity

1

Base Price: ₹ 37,113.00

GST (18%): ₹ 6,680.34

Total Price: ₹ 43,793.34

Antigen

iNOS

Classification

Monoclonal

Concentration

0.2 mg/mL

Formulation

PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.

P29477

Gene Symbols

Nos2

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

18126

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Form

Liquid

Applications

Flow Cytometry

Clone

CXNFT

Conjugate

APC

Gene

Nos2

Gene Alias

Hepatocyte NOS; hepatocytes; HEP-NOS; inducible nitric oxide synthase; inducible NO synthase; Inducible NOS; iNos; i-NOS; Inosl; MAC-NOS; macrophage NOS; nitric oxide synthase 2; nitric oxide synthase 2, inducible; nitric oxide synthase 2, inducible, macrophage; nitric oxide synthase 2A (inducible, hepatocytes); nitric oxide synthase, inducible; nitric oxide synthase, macrophage; nitric oxide synthase-inducible; NOS; NOS type II; NOS, type II; Nos2; Nos-2; Nos2a; NOS-II; OTTMUSP00000000202; peptidyl-cysteine S-nitrosylase NOS2

Host Species

Rat

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Mouse

Product Type

Antibody

Isotype

IgG2a κ

Description

  • Description: This CXNFT monoclonal antibody reacts to mouse NOS2 (inducible NOS, iNOS)
  • Nitric oxide synthase enzymes catalyze the formation of nitric oxide from L-arginine through an NADPH- and oxygen-dependent mechanism
  • There are three isoforms of NOS that are encoded by three separate genes
  • NOS1 (neuronal NOS, nNOS) and NOS3 (endothelial NOS, eNOS) are constitutively expressed, while NOS2 is induced in response to bacterial endotoxins and inflammatory cytokines such as IFN gamma and TNF alpha
  • NOS2 is expressed by myeloid-derived suppressor cells and M1 macrophages but not alternatively activated M2 macrophages
  • NOS enzymes are functionally active only when they form homodimers, and dimerization of NOS2 occurs at steady-state concentrations of free Ca2+ such that NOS2 is functionally active when it is produced
  • Applications Reported: This CXNFT antibody has been reported for use in intracellular staining followed by flow cytometric analysis
  • Applications Tested: This CXNFT antibody has been tested by intracellular staining and flow cytometric analysis of LPS-stimulated mouse thioglycolate-elicited peritoneal exudate cells using the Intracellular Fixation and Permeabilization Buffer Set (cat
  • 88-8824) and protocol
  • Please refer to Best Protocols: Protocol A: Two step protocol for (cytoplasmic) intracellular proteins located under the Resources Tab online
  • This can be used at less than or equal to 0.06 μg per test
  • iNOS Monoclonal antibody specifically detects iNOS in Mouse samples
  • It is validated for Flow Cytometry.