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50-112-3790

CD195 (CCR5) Monoclonal Antibody (HM-CCR5 (7A4)), PerCP-eFluor™ 710, eBioscience™, Invitrogen™

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 50-112-3790-Each-of-1 In Stock ₹ 33,731.00

50-112-3790 - Each of 1

₹ 33,731.00

In Stock

Quantity

1

Base Price: ₹ 33,731.00

GST (18%): ₹ 6,071.58

Total Price: ₹ 39,802.58

Antigen

CD195 (CCR5)

Classification

Monoclonal

Concentration

0.2 mg/mL

Formulation

PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.

P51682

Gene Symbols

CCR5

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

12774

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Form

Liquid

Applications

Flow Cytometry

Clone

HM-CCR5 (7A4)

Conjugate

PerCP-eFluor 710

Gene

CCR5

Gene Alias

AM4-7; C-C chemokine receptor type 5; C-C CKR-5; C-C motif chemokine receptor 5 (gene/pseudogene); C-C motif chemokine receptor 5 A159A; CCCKR5; CC-CKR-5; Ccr5; CCR-5; CD195; CD195 antigen; chemokine (C-C motif) receptor 5; chemokine (C-C) receptor 5; chemokine receptor CCR5; chemr13; CKR5; CKR-5; Cmkbr5; HIV-1 fusion coreceptor; IDDM22; MIP-1 alpha receptor

Host Species

Armenian Hamster

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Mouse

Product Type

Antibody

Isotype

IgG

Description

  • Description: CCR5 is the major co-receptor for macrophage-tropic isolates of HIV-1
  • CCR5, also known as CD195, is a seven transmembrane chemokine receptor capable of binding RANTES, MIP-1 alpha and MIP-1 beta
  • Knockout mice show a decreased recruitment of macrophages and increased susceptibility to infection
  • Protein and mRNA has been found in macrophages from thioglycolate-treated and activated T cells
  • The HM-CCR5(7A4) monoclonal antibody binds the N terminal extracellular domain of mouse CCR5 with no crossreactivity to human CCR5
  • Applications Reported: This HM-CCR5 (7A4) antibody has been reported for use in flow cytometric analysis
  • Applications Tested: This HM-CCR5 (7A4) antibody has been tested by flow cytometric analysis of mouse thioglycolated- induced peritoneal exudate cells
  • This can be used at less than or equal to 0.25 μg per test
  • A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
  • Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
  • It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest
  • PerCP-eFluor™ 710 can be used in place of PE-Cy5, PE-Cy5.5 or PerCP-Cy5.5
  • PerCP-eFluor™ 710 emits at 710 nm and is excited with the blue laser (488 nm)
  • Please make sure that your instrument is capable of detecting this fluorochrome
  • CD195 (CCR5) Monoclonal antibody specifically detects CD195 (CCR5) in Mouse samples
  • It is validated for Flow Cytometry.