50-112-4333
CD301b (MGL2) Monoclonal Antibody (11A10-B7), eFluor™ 660, eBioscience™, Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-112-4333-Each-of-1 | In Stock | ₹ 34,354.00 |
50-112-4333 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 34,354.00
GST (18%): ₹ 6,183.72
Total Price: ₹ 40,537.72
Antigen
CD301b (MGL2)
Classification
Monoclonal
Concentration
0.2 mg/mL
Formulation
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.
0
Gene Symbols
Mgl2
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
216864
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Applications
Flow Cytometry
Clone
11A10-B7
Conjugate
eFluor 660
Gene
Mgl2
Gene Alias
CD301; CD301b; macrophage galactose N-acetyl-galactosamine specific lectin 2; macrophage galactose-type C-type lectin 2; Mgl2
Host Species
Rat
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Mouse
Product Type
Antibody
Isotype
IgG2a λ
Related Products
Description
- Description: The monoclonal antibody 11A10-B7 recognizes mouse CD301b
- CD301b is also known as macrophage galactose-type C-type lectin 2 (MGL2)
- CD301b expression is restricted to dermal dendritic cells, connection tissue, and bone marrow derived dendritic cells
- Macrophages also express CD301b at low levels
- CD301b contains a single carbohydrate recognition domain that recognizes protein antigens that have a galactose and N-acetylgalactosamine (Gal/GalNAc)
- Gal/GalNAc protein antigens are efficiently internalized through CD301b and presented to antigen specific CD4+ cells via MHC Class II
- CD301b+ dendritic cells are believed to play an important role in TH2 priming
- Applications Reported: This 11A10-B7 antibody has been reported for use in flow cytometric analysis
- Applications Tested: This 11A10-B7 antibody has been tested by flow cytometric analysis of mouse skin draining lymph node cells
- This can be used at less than or equal to 0.25 μg per test
- A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
- Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
- It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest
- eFluor™ 660 is a replacement for Alexa Fluor™ 647
- eFluor™ 660 emits at 659 nm and is excited with the red laser (633 nm)
- CD301b is also known as macrophage galactose-type C-type lectin 2 (MGL2)
- CD301b expression is restricted to dermal dendritic cells, connection tissue, and bone marrow derived dendritic cells
- Macrophages also express CD301b at low levels
- CD301b contains a single carbohydrate recognition domain that recognizes protein antigens that have a galactose and N-acetylgalactosamine (Gal/GalNAc)
- Gal/GalNAc protein antigens are efficiently internalized through CD301b and presented to antigen specific CD4+ cells via MHC Class II
- CD301b+ dendritic cells are believed to play an important role in TH2 priming.