50-112-4374
EOMES Monoclonal Antibody (Dan11mag), eFluor™ 660, eBioscience™, Invitrogen™
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each | 50-112-4374-Each | In Stock | ₹ 14,386.85 |
50-112-4374 - Each
In Stock
Quantity
1
Base Price: ₹ 14,386.85
GST (18%): ₹ 2,589.633
Total Price: ₹ 16,976.483
Antigen
EOMES
Classification
Monoclonal
Concentration
0.2 mg/mL
Formulation
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.
O54839
Gene Symbols
Eomes
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
13813
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Applications
Flow Cytometry
Clone
Dan11mag
Conjugate
eFluor 660
Gene
Eomes
Gene Alias
C77258; EOMES; eomesodermin; eomesodermin homolog; eomesodermin homolog (Xenopus laevis); T-box brain protein 2; T-box transcription factor; TBR2; TBR-2; T-brain-2
Host Species
Rat
Quantity
25 μg
Primary or Secondary
Primary
Target Species
Mouse
Product Type
Antibody
Isotype
IgG2a κ
Related Products
Description
- Description: This Dan11mag antibody recognizes Eomesodermin (EOMES), also known as T-box brain 2 (TBR2)
- Eomes is a T-box transcription factor that is highly homologous to T-bet, which is essential during trophoblast development and gastrulation in most vertebrates
- In the immune system, Eomes controls the differentiation of effector and memory CD8+ T cells, as well as natural killer (NK) cells
- Expression of Eomes in these cells correlates with high expression of CD122, the common beta-chain of the IL-2R and IL-15R
- Applications Reported: This Dan11mag antibody has been reported for use in intracellular staining followed by flow cytometric analysis
- Applications Tested: This Dan11mag antibody has been tested by intracellular staining and flow cytometric analysis of mouse splenocytes using the Foxp3/Transcription Factor Buffer Set (cat
- 00-5523) and protocol
- Please see Best Protocols Section (Staining intracellular Antigens for Flow Cytometry) for staining protocol (refer to Protocol B: One-step protocol for intracellular (nuclear) proteins)
- This can be used at less than or equal to 0.25 μg per test
- A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
- Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
- It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest
- TBR2 is a member of a conserved protein family that shares a common DNA-binding domain, the T-box
- T-box genes encode transcription factors involved in the regulation of developmental processes
- A similiar protein disrupted in mice is shown to be essential during trophoblast development and gastrulation
- TBR2 plays a role in brain development and is required for the specification and the proliferation of the intermediate progenitor cells and their progeny in the cerebral cortex.