Galectin 9 Monoclonal Antibody (9M1-3), eFluor™ 660, eBioscience™, Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-112-8661-Each-of-1 | In Stock | ₹ 37,113.00 |
50-112-8661 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 37,113.00
GST (18%): ₹ 6,680.34
Total Price: ₹ 43,793.34
Antigen
Galectin 9
Classification
Monoclonal
Concentration
5 μL/Test
Formulation
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.
O00182
Gene Symbols
Lgals9
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
3965
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Applications
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone
9M1-3
Conjugate
eFluor 660
Gene
Lgals9
Gene Alias
36 kDa beta-galactoside-binding lectin; AA407335; AI194909; AI265545; ecalectin; Gal9; gal-9; galectin 9; Galectin9; galectin-9; HOM HD 21; HUAT; Lectin galactose binding soluble 9 (Galectin-9); lectin, galactose binding, soluble 5; lectin, galactose binding, soluble 9; Lectin, galactose binding, soluble 9 (Galectin-9); lectin, galactoside binding soluble 9; lectin, galactoside-binding, soluble, 9; LGALS35; Lgals5; LGALS9; LGALS9A; tumor antigen HOM-HD-21; UAT; urate transporter/channel; urate transporter/channel protein
Host Species
Mouse
Quantity
100 Tests
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1 κ
Related Products
Description
- Description: This 9M1-3 monoclonal antibody reacts with human Galectin-9
- Galectin-9 is one of fifteen members of the galectin family of glycan-binding proteins
- It is expressed on activated T helper cells and Foxp3+ T regulatory cells and plays a critical role in the regulation of immune function
- Interaction of Galectin-9 with its ligand, TIM3, induces apoptosis in Th1 and Th17, inhibits Th17 polarization and IFN gamma expression, and drives Treg expansion
- Galectin-9 is also thought to contribute to the survival and expansion of some tumors by inhibiting the anti-tumor response and promoting immune evasion
- Along with Galectin-1 and Galectin-3, high levels of Galectin-9 expression are associated with poor cancer prognosis, making these potential therapeutic targets
- Applications Reported: This 9M1-3 antibody has been reported for use in flow cytometric analysis
- Applications Tested: This 9M1-3 antibody has been pre-titrated and tested by flow cytometric analysis of normal human peripheral blood cells
- This can be used at 5 μL (0.25 μg) per test
- A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
- Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
- eFluor™ 660 is a replacement for Alexa Fluor™ 647
- eFluor™ 660 emits at 659 nm and is excited with the red laser (633 nm)
- The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions
- The protein encoded by this gene is an S-type lectin
- It is overexpressed in Hodgkin's disease tissue and might participate in the interaction between the H and RS cells with their surrounding cells and might thus play a role in the pathogenesis of this disease and/or its associated immunodeficiency
- Multiple alternatively spliced transcript variants have been found for this gene.