50-112-9269

CD337 (NKp30) Monoclonal Antibody (AF29-4D12), PE-Cyanine7, eBioscience™, Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each of 1 50-112-9269-Each-of-1 In Stock ₹ 35,867.00

50-112-9269 - Each of 1

₹ 35,867.00

In Stock

Quantity

1

Base Price: ₹ 35,867.00

GST (18%): ₹ 6,456.06

Total Price: ₹ 42,323.06

Antigen

CD337 (NKp30)

Classification

Monoclonal

Concentration

5 μL/Test

Formulation

PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.

O14931, Q8MJ02

Gene Symbols

Ncr3

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

259197, 715574

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Form

Liquid

Applications

Flow Cytometry

Clone

AF29-4D12

Conjugate

PE-Cyanine7

Gene

Ncr3

Gene Alias

1C7; Activating natural killer receptor p30; activating NK-A1 receptor; CD337; LY117; lymphocyte antigen 117; MALS; Natural cytotoxicity triggering receptor 3; natural killer cell p30-related protein; natural killer cell receptor; Ncr3; NK receptor 1c7; Nkp30; NK-p30; NKp30S; NKp30v1; NKp30v1ED

Host Species

Mouse

Quantity

100 Tests

Primary or Secondary

Primary

Target Species

Human, Non-human Primate, Rhesus Monkey

Product Type

Antibody

Isotype

IgG1 κ

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Description

  • Description: This AF29-4D12 monoclonal antibody reacts with human CD337, which is also known as NKp30
  • Expressed on NK cells, CD337 is the predomit member of the natural cytotoxicity receptor family that also includes NKp46 and NKp44
  • CD337 is involved in activating and expanding resting NK cells following interaction with dendritic cells to eliminate tumor, virus-infected, and immature dendritic cells
  • Several ligands for this receptor have been reported, including B7-H6
  • The AF29-4D12 antibody has been reported to crossreact to rhesus macaque
  • Applications Reported: This AF29-4D12 antibody has been reported for use in flow cytometric analysis
  • Applications Tested: This AF29-4D12 antibody has been pre-titrated and tested by flow cytometric analysis of normal human peripheral blood cells
  • This can be used at 5 μL (0.06 μg) per test
  • A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
  • Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
  • Light sensitivity: This tandem dye is sensitive photo-induced oxidation
  • Please protect this vial and stained samples from light
  • Fixation: Samples can be stored in IC Fixation Buffer (cat
  • 00-8222) (100 μL cell sample + 100 μL IC Fixation Buffer) or 1-step Fix/Lyse Solution (cat
  • The protein encoded by this gene is a natural cytotoxicity receptor (NCR) that may aid NK cells in the lysis of tumor cells
  • The encoded protein interacts with CD3-zeta (CD247), a T-cell receptor
  • A single nucleotide polymorphism in the 5' untranslated region of this gene has been associated with mild malaria suceptibility
  • Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, May 2010].