50-112-9273

CD32 Monoclonal Antibody (6C4 (CD32)), PE, eBioscience™, Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each of 1 50-112-9273-Each-of-1 In Stock ₹ 31,684.00

50-112-9273 - Each of 1

₹ 31,684.00

In Stock

Quantity

1

Base Price: ₹ 31,684.00

GST (18%): ₹ 5,703.12

Total Price: ₹ 37,387.12

Antigen

CD32

Classification

Monoclonal

Concentration

5 μL/Test

Formulation

PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.

P12318, P31994, P31995

Gene Symbols

FCGR2A, FCGR2B, FCGR2C

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

2212, 2213, 9103

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Form

Liquid

Applications

Flow Cytometry

Clone

6C4 (CD32)

Conjugate

PE

Gene

FCGR2B

Gene Alias

CD32; CD32 receptor 2; CD32 receptor 2a; CD32A; CD32B; CD32C; CDW32; Fc fragment of IgG receptor IIa; Fc fragment of IgG receptor IIb; Fc fragment of IgG receptor IIc (gene/pseudogene); Fc fragment of IgG, low affinity II, receptor for (CD32); Fc fragment of IgG, low affinity IIa, receptor (CD32); Fc fragment of IgG, low affinity IIa, receptor for (CD32); Fc fragment of IgG, low affinity IIb, receptor (CD32); Fc fragment of IgG, low affinity IIb, receptor for (CD32); Fc fragment of IgG, low affinity IIc, receptor for (CD32); Fc gamma receptor II; Fc gamma receptor IIa; Fc gamma receptor IIb; Fc gamma receptor IIC; Fc gamma RIIb; FCG2; Fc-gamma receptor II; fc-gamma RII; Fc-gamma RII-a; fc-gamma RII-b; Fc-gamma RII-c; fc-gamma-RIIa; Fc-gamma-RIIb; fc-gamma-RIIc; Fc-gamma-RII-D; FcGR; FCGR2; FCGR2A; FCGR2A1; FCGR2B; FCGR2C; fcRII; fcRII-a; fcRII-b; FCRIIC; FGFR2B; IGFR2; IgG Fc fragment receptor; IgG Fc gamma receptor II; igG Fc receptor II; IgG Fc receptor II-a; igG Fc receptor II-b; IgG Fc receptor II-c; Immunoglobulin G Fc receptor II; immunoglobulin G Fc receptor II-c; low affinity immunoglobulin gamma Fc region receptor II; Low affinity immunoglobulin gamma Fc region receptor II-a; low affinity immunoglobulin gamma Fc region receptor II-b; Low affinity immunoglobulin gamma Fc region receptor II-c; MGC23887; MGC30032; RP11-5K23.6; soluble receptor; boFcRII-2

Host Species

Mouse

Quantity

100 Tests

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1 κ

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Description

  • Description: This 6C4 monoclonal antibody reacts with human CD32 (also known as Fc gamma RII)
  • This antibody recognizes two isoforms of the receptor, Fc gamma RIIA and Fc gamma RIIB
  • These 40-kDa polymorphic transmembrane glycoproteins are expressed on B cells, granulocytes, monocytes, macrophages, and platelets
  • Moreover, these receptors are detected on natural killer cells
  • CD32 enables interaction between Fc gamma RII-expressing cells and opsonized antigen or IgG-containing immune complexes
  • Both receptors exhibit low affinity towards IgG and play a role in inflammation and autoimmune disease
  • This clone has been reported to inhibit Ig binding in a rosette blocking assay
  • Applications Reported: This 6C4 (CD32) antibody has been reported for use in flow cytometric analysis
  • Applications Tested: This 6C4 (CD32) antibody has been pre-titrated and tested by flowcytometric analysis of normal human peripheral blood cells
  • This can be used at 5 μL (0.125 μg) per test
  • A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
  • Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
  • Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser
  • Filtration: 0.2 μm post-manufacturing filtered
  • This gene encodes one member of a family of immunoglobulin Fc receptor genes found on the surface of many immune response cells
  • The protein encoded by this gene is a cell surface receptor found on phagocytic cells such as macrophages and neutrophils, and is involved in the process of phagocytosis and clearing of immune complexes
  • Alternative splicing results in multiple transcript variants.