50-112-9462
IL-10 Monoclonal Antibody (JES3-9D7), Functional Grade, eBioscience™, Invitrogen™
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-112-9462-Each-of-1 | In Stock | ₹ 32,930.00 |
50-112-9462 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 32,930.00
GST (18%): ₹ 5,927.40
Total Price: ₹ 38,857.40
Antigen
IL-10
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with no preservative; pH 7.2
Gene Accession No.
P22301
Gene Symbols
IL10
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
3586
Content And Storage
4° C
Form
Liquid
Applications
ELISA, Functional Assay, Neutralization
Clone
JES3-9D7
Conjugate
Functional Grade
Gene
IL10
Gene Alias
CSIF; cytokine; Cytokine synthesis inhibitory factor; GVHDS; H-IL-10; il 10; IL10; IL-10; IL-10 precursor; IL10A; IL10X; ILN; Interleukin; interleukin 10; Interleukin10; interleukin-10; MGC126450; MGC126451; RP11-262N9.1; T-cell growth inhibitory factor; TGIF
Host Species
Rat
Quantity
500 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1 κ
Related Products
Description
- Description: The JES3-9D7 monoclonal antibody reacts with human interleukin-10 (IL-10)
- Applications Reported: The JES3-9D7 antibody has been reported for use in ELISA capture, ELISPOT capture, neutralization, and intracellular staining for flow cytometric analysis
- Applications Tested: The JES3-9D7 antibody has been tested for neutralizing IL-10 binding and biological activity
- Storage and handling: Use in a sterile environment
- Filtration: 0.2 μm post-manufacturing filtered
- Purity: Greater than 90%, as determined by SDS-PAGE
- Endotoxin Level: Less than 0.001 ng/μg antibody, as determined by LAL assay
- Aggregation: Less than 10%, as determined by HPLC
- IL-10 encodes a protein that acts as a cytokine and is primarily produced by monocytes, with some production by lymphocytes
- This cytokine has various effects on immunoregulation and inflammation, including down-regulating the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages
- It also enhances B cell survival, proliferation, and antibody production
- Additionally, IL-10 can block NF-kappa B activity and is involved in the regulation of the JAK-STAT signaling pathway
- Knockout studies in mice have suggested that this cytokine is an essential immunoregulator in the intestinal tract
- Mutations in this gene have been associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis
- Diseases associated with IL10 include Graft-Versus-Host Disease and Human Immunodeficiency Virus Type 1.