50-112-9509
CD39 Monoclonal Antibody (eBioA1 (A1)), FITC, eBioscience™, Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-112-9509-Each-of-1 | In Stock | ₹ 24,386.00 |
50-112-9509 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 24,386.00
GST (18%): ₹ 4,389.48
Total Price: ₹ 28,775.48
Antigen
CD39
Classification
Monoclonal
Concentration
5 μL/Test
Formulation
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.
P49961
Gene Symbols
ENTPD1
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
953
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Applications
Flow Cytometry
Clone
eBioA1 (A1)
Conjugate
FITC
Gene
ENTPD1
Gene Alias
2610206B08Rik; AA408691; ATPDase; Cd39; CD39 antigen; DKFZp686D194; DKFZp686I093; ecto-apyrase; Ecto-ATP diphosphohydrolase 1; ecto-ATPase 1; ecto-ATPDase 1; Ectonucleoside triphosphate diphosphohydrolase 1; ENTPD1; FLJ40921; FLJ40959; Lymphoid cell activation antigen; NTPDase 1; NTPDase-1; SPG64
Host Species
Mouse
Quantity
100 Tests
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1 κ
Related Products
Description
- Description: The eBioA1 monoclonal antibody reacts with human CD39 also known as ectonucleoside triphosphate diphosphohydrolase 1 (ENTPD1) or NTPDase
- CD39 is an integral membrane protein with two transmembrane domains and exists as a homotetramer
- It is the most prominent ectoenzyme of the immune system
- The function of CD39 is to effectively remove toxic extracellular ATP by converting it to ADP or AMP
- CD39 is thought to work together with CD73 to hydrolyze ATP and has been well characterized on Langerhans cells
- Expression of CD39 was originally identified on activated lymphocytes
- Expression is also found on a subset of T cells, B cells and dendritic cells as well as weak staining on monocytes and granulocytes
- Recently, CD39 and CD73 have been found on regulatory T cells (Treg)
- Expression of CD39 on Treg may facilitate their entry into inflamed areas where high levels of ATP are present
- Expression of CD39 on Foxp3+CD4+ cells ranges from 25-45%
- Applications Reported: This eBioA1 (A1) antibody has been reported for use in flow cytometric analysis
- Applications Tested: This eBioA1 (A1) antibody has been pre-titrated and tested by flow cytometric analysis of normal human peripheral blood cells
- This can be used at 5 μL (0.25 μg) per test
- A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
- Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
- CD39 cell surface antigen is a 70-100kD molecule expressed on peripheral blood B cells, monocytes, T cell clones, and also weakly expressed on granulocytes
- CD39 has intrinsic ecto-ATPase activity
- Expression of CD39 is induced on T cells and increased on B cells as a late activation antigen.