50-112-9682

CD11c Monoclonal Antibody (3.9), PE-Cyanine7, eBioscience™, Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each of 1 50-112-9682-Each-of-1 In Stock ₹ 35,333.00

50-112-9682 - Each of 1

₹ 35,333.00

In Stock

Quantity

1

Base Price: ₹ 35,333.00

GST (18%): ₹ 6,359.94

Total Price: ₹ 41,692.94

Antigen

CD11c

Classification

Monoclonal

Concentration

5 μL/Test

Formulation

PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.

P20702

Gene Symbols

Itgax

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

3687

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Form

Liquid

Applications

Flow Cytometry

Clone

3.9

Conjugate

PE-Cyanine7

Gene

Itgax

Gene Alias

AI449405; CD11 antigen-like family member C; CD11c; CD11C (p150) alpha polypeptide; complement component 3 receptor 4 subunit; complement receptor 4; Cr4; integrin alpha X; integrin alpha-X; integrin aX; integrin subunit alpha X; integrin, alpha X; integrin, alpha X (antigen CD11C (p150), alpha polypeptide); integrin, alpha X (complement component 3 receptor 4 subunit); Itgax; Leu M5; leu M5, alpha subunit; leukocyte adhesion glycoprotein p150,95 alpha chain; Leukocyte adhesion receptor p150,95; leukocyte surface antigen p150,95, alpha subunit; myeloid membrane antigen, alpha subunit; N418; p150 95 integrin alpha chain; RGD1561123; SLEB6

Host Species

Mouse

Quantity

100 Tests

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1 κ

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Description

  • Description: The 3.9 monoclonal antibody reacts with human CD11c, the 150 kDa integrin alpha X chain
  • CD11c non-covalently associates with beta2 integrin to form the CD11c/CD18 heterodimer
  • This complex is expressed on monocytes, granulocytes, macrophages, NK, dendritic cells and subset of T and B lymphocytes
  • CD11c/CD18 binds to CD54, iC3b and fibrinogen and plays a role in leukocyte adhesive interactions
  • Applications Reported: This 3.9 antibody has been reported for use in flow cytometric analysis
  • Applications Tested: This 3.9 antibody has been pre-titrated and tested by flow cytometric analysis of normal human peripheral blood cells
  • This can be used at 5 μL (1 μg) per test
  • A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
  • Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
  • Light sensitivity: This tandem dye is sensitive photo-induced oxidation
  • Please protect this vial and stained samples from light
  • Fixation: Samples can be stored in IC Fixation Buffer (cat
  • 00-8222) (100 μL cell sample + 100 μL IC Fixation Buffer) or 1-step Fix/Lyse Solution (cat
  • 00-5333) for up to 3 days in the dark at 4°C with minimal impact on brightness and FRET efficiency/compensation
  • CD11, along with CD18, form a heterodimer adhesion molecule
  • In particular, CD11 is composed of CD11a, CD11b and CD11c
  • CD11a is a leukocyte marker that is expressed in B and T lymphocytes, macrophages, monocytes, neutrophils, basophils and eosinophils
  • CD11b is primarily expressed by monocytes, macrophages, natural killer cells, some B and T-cells, and granulocytes
  • CD11c is expressed in monocytes, macrophages, natural killer cells, some granulocytes and less so in a subset of lymphocytes.