ICAM-1 Monoclonal Antibody (YN1/1.7.4), Pacific Blue™, Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-113-7029-Each-of-1 | In Stock | ₹ 25,276.00 |
50-113-7029 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 25,276.00
GST (18%): ₹ 4,549.68
Total Price: ₹ 29,825.68
Antigen
ICAM-1
Classification
Monoclonal
Concentration
0.5 mg/mL
Formulation
PBS with <0.1% sodium azide
Gene Accession No.
P13597
Gene Symbols
ICAM1
Immunogen
Mouse NS-1 cells
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Mouse, Porcine
Product Type
Antibody
Isotype
IgG2b κ
Applications
Flow Cytometry
Clone
YN1/1.7.4
Conjugate
Pacific Blue
Gene
ICAM1
Gene Alias
BB2; CD54; cell surface glycoprotein P3.58; Human rhinovirus receptor; ICAM; Icam1; ICAM-1; ICAM-1; CD54 homolog; Intercellular adhesion molecule 1; intercellular adhesion molecule 1 (CD54), human rhinovirus receptor; intercellular adhesion molecule-1; intercellular adhesion molecule-1 precursor; Ly 47; Ly-47; major group rhinovirus receptor; MALA2; MALA-2; MyD10; P3.58; sCD54; soluble CD54; Surface antigen of activated B cells
Host Species
Rat
Purification Method
purified
Regulatory Status
RUO
Gene ID (Entrez)
15894, 396750
Content And Storage
4° C, store in dark
Form
Liquid
Related Products
Description
- ICAM-1 (CD54) is an 85-110 kDa single-chain type 1 integral membrane glycoprotein with an extracellular domain of five immunoglobulin superfamily repeats, a transmembrane region and a cytoplasmic domain
- ICAM-1 has 7 potential N-linked glycosylation sites and shares considerable amino acid sequence homology with ICAM-3 (CD50) and ICAM-2 (CD102)
- ICAM-1 binds to integrins of type CD11a/CD18 (leukocyte adhesion molecule, LFA-1), or CD11b/CD18 (Mac-1) and is exploited by Rhinovirus as a receptor
- ICAM-1 is expressed by activated endothelial cells and detected on epithelial cells, fibroblasts, chondrocytes, B lymphocytes, T lymphocytes (low), monocytes, macrophages, dendritic cells and neutrophils, with lower levels that increase upon inflammation
- ICAM-1 is also detected in some carcinoma and melanoma cells
- Soluble ICAM-1 is detectable in the plasma and is elevated in patients with various inflammatory syndromes.