50-113-7435

CTLA-4 Monoclonal Antibody (1B8), FITC, Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each of 1 50-113-7435-Each-of-1 In Stock ₹ 47,170.00

50-113-7435 - Each of 1

₹ 47,170.00

In Stock

Quantity

1

Base Price: ₹ 47,170.00

GST (18%): ₹ 8,490.60

Total Price: ₹ 55,660.60

Antigen

CTLA-4

Classification

Monoclonal

Concentration

0.5 mg/mL

Formulation

PBS with <0.1% sodium azide

Gene Accession No.

P09793

Gene Symbols

CTLA4

Immunogen

Mouse CD152 (CTLA-4). from Extracellular portion of murine CTLA-4 fused to a murine IgG2a

Quantity

500 μg

Primary or Secondary

Primary

Target Species

Mouse

Product Type

Antibody

Isotype

IgG1

Applications

ELISA, Flow Cytometry

Clone

1B8

Conjugate

FITC

Gene

CTLA4

Gene Alias

ALPS5; CD; CD152; CD152 antigen; CD152 isoform; CD152 protein; CD152 protein precursor; celiac disease 3; CELIAC3; Ctla4; CTLA-4; cytotoxic T lymphocyte associated antigen 4 short spliced form; cytotoxic T-lymphocyte associated protein 4; cytotoxic T-lymphocyte protein 4; cytotoxic T-lymphocyte protein 4 isoform CTLA4-TM; cytotoxic T-lymphocyte-associated antigen 4; cytotoxic T-lymphocyte-associated protein 4; cytotoxic T-lymphocyte-associated serine esterase-4; EGK_04712; GRD4; GSE; ICOS; IDDM12; insulin-dependent diabetes mellitus 12; ligand and transmembrane spliced cytotoxic T lymphocyte associated antigen 4; Ly-56; sCTLA4; soluble form; transmembrane form

Host Species

Armenian Hamster

Purification Method

purified

Regulatory Status

RUO

Gene ID (Entrez)

12477

Content And Storage

4° C, store in dark

Form

Liquid

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Description

  • CTLA4 (Cytotoxic T-Lymphocyte Antigen 4) is a CD28-family receptor expressed on mainly CD4+ T cells
  • It binds the same ligands as CD28 (CD80 and CD86 on B cells and dendritic cells), but with higher affinity than CD28
  • However, in contrast to CD28 which enhances cell function when bound at the same time as the T cell receptor, CTLA4 inhbits the T cell and prevents it from functioning
  • Intracellular CTLA4 is also found in regulatory T cells and may be important to their function.