50-113-7638
CD45.2 Monoclonal Antibody (104), Alexa Fluor™ 647, Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-113-7638-Each-of-1 | In Stock | ₹ 13,528.00 |
50-113-7638 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 13,528.00
GST (18%): ₹ 2,435.04
Total Price: ₹ 15,963.04
Antigen
CD45.2
Classification
Monoclonal
Concentration
0.5 mg/mL
Formulation
PBS with <0.1% sodium azide
Gene Accession No.
P06800
Gene Symbols
Ptprc
Immunogen
B10.S mouse thymocytes and splenocytes.
Quantity
25 μg
Primary or Secondary
Primary
Target Species
Mouse
Product Type
Antibody
Isotype
IgG2a κ
Applications
Flow Cytometry
Clone
104
Conjugate
Alexa Fluor 647
Gene
Ptprc
Gene Alias
B220; Cd45; CD45 antigen; CD45R; GP180; LCA; L-CA; leukocyte common antigen; loc; LY5; Ly-5; lymphocyte antigen 5; lymphocyte common antigen; Lyt-4; protein tyrosine phosphatase, receptor type, C; Ptprc; Receptor-type tyrosine-protein phosphatase C; T200; T200 glycoprotein
Host Species
Mouse
Purification Method
purified
Regulatory Status
RUO
Gene ID (Entrez)
19264
Content And Storage
4° C, store in dark
Form
Liquid
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Description
- CD45.2 (LCA, leukocyte common antigen) is a receptor-type protein tyrosine phosphatase ubiquitously expressed in all nucleated hematopoietic cells, comprising approximately 10% of all surface proteins in lymphocytes
- CD45.2 glycoprotein is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases
- CD45.2 protein exists as multiple isoforms as a result of alternative splicing; these isoforms differ in their extracellular domains, whereas they share identical transmembrane and cytoplasmic domains
- These isoforms differ in their ability to translocate into the glycosphingolipid-enriched membrane domains and their expression depends on cell type and physiological state of the cell
- Besides the role in immunoreceptor signaling, CD45.2 is important in promoting cell survival by modulating integrin-mediated signal transduction pathway and is also involved in DNA fragmentation during apoptosis
- CD45RA is an isoform of the CD45 complex and has restricted expression between different subtypes of lymphoid cells.